Results 101 to 110 of about 670,278 (352)
Biology of Sex Differences, 2019 Background The obesity-related risk of developing metabolic syndrome is higher in males than in females of reproductive age, likely due to estrogen-mediated reduced adipose tissue inflammation and fibrosis with hypertrophied adipocytes.
Sujoy Ghosh +7 more
doaj +1 more source
Comparison between dual-purpose and specialized dairy cattle in pasture-based systems: change in body condition, locomotion score and cleanliness from summer to winter season [PDF]
, 2017 This study is an exploratory research comparing the changes of body condition score, locomotion score and cleanliness score between pasture and indoor season in purebred Dutch Friesian, 75% Dutch Friesian, 50% Dutch Friesian, Holstein Bakels and Brown ...
Scholl, Francisca
core
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
Brown and Beige Fat: Therapeutic Potential in Obesity
Indonesian Biomedical Journal, 2014 BACKGROUND: The epidemic of obesity and type 2 diabetes presents a serious challenge to scientific and biomedical communities worldwide. There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the ...
Anna Meiliana, Andi Wijaya
doaj +1 more source
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor? [PDF]
, 2013 FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain.
Erickson, HP
core +1 more source
Advanced Science, EarlyView.Compared to a healthy random nanofibrous fibronectin microenvironment, a fibrotic aligned nanofibrous fibronectin microenvironment employs a specific integrin, α5β1 integrin, to activate early pro‐fibrotic fibroblast behaviors and later fibrotic fibroblast tissue formation with cell/F‐actin alignment, α‐SMA expression, and cell‐driven aligned ...
Doğuhan Beyatlı +3 more
wiley +1 more source
Glucocorticoid Receptor and Adipocyte Biology. [PDF]
, 2018 Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A +2 more
core +2 more sources
Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
The role of DNA methylation in thermogenic adipose biology. [PDF]
, 2019 The two types of thermogenic fat cells, beige and brown adipocytes, play a significant role in regulating energy homeostasis. Their development and thermogenesis are tightly regulated by dynamic epigenetic mechanisms, which could potentially be targeted ...
Kang, Sona, Xiao, Han
core +1 more source
Advanced Science, EarlyView.Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan +11 more
wiley +1 more source