Results 71 to 80 of about 1,970,039 (250)

Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation

Nature Communications, 2017
Browning of subcutaneous white fat (iWAT) involves several reprograming events, but the underlying mechanisms are incompletely understood. Here we show that the transcription factor Hlx is selectively expressed in brown adipose tissue (BAT) and iWAT, and
Lei Huang, Dongning Pan, Qingbo Chen, L. Zhu, Jianhong Ou, M. Wabitsch, Yong-Xu Wang   +6 more
semanticscholar   +1 more source

Benefits of Soybean Pulp and Brown Rice Flour for Improving Carcass Performance and Reducing Fat Content in Peking Duck

Jurnal Agripet
Soybean pulp and brown rice flour have a high protein content to increase the nutrients of Pekingese duck feed. The experimental research method used a Factorial Design with 5 treatments and 5 replicates, the details of the treatment were as follows ...
Siti Rani Ayuti, Mudastsir Mudastsir, Mira Sukma Delima, Teuku Reza Ferasyi, Muslim Akmal, Novia Qomariyah, Mira Andriani, Sadarman Sadarman, Filphin Adolfin Amalo, Djoko Subagyo   +9 more
doaj   +1 more source

The brown adipocyte differentiation pathway in birds: An evolutionary road not taken

BMC Biology, 2008
Background Thermogenic brown adipose tissue has never been described in birds or other non-mammalian vertebrates. Brown adipocytes in mammals are distinguished from the more common white fat adipocytes by having numerous small lipid droplets rather than ...
Kumaratilake Jaliya S, Mezentseva Nadejda V, Newman Stuart A   +2 more
doaj   +1 more source

Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity

Nature Communications, 2016
Brown adipose tissue (BAT) dissipates energy and its activity correlates with leanness in human adults. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography coupled with computer tomography (PET/CT) is still the standard for measuring BAT ...
Yong Chen, J. J. Buyel, Mark J. W. Hanssen, Franziska Siegel, Ruping Pan, Jennifer Naumann, Michael J. Schell, A. A. van der Lans, C. Schlein, H. Froehlich, J. Heeren, K. Virtanen, W. D. van Marken Lichtenbelt, A. Pfeifer   +13 more
semanticscholar   +1 more source

Optical imaging for brown or beige adipose tissue

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Currently, one in three adults worldwide may be obese or overweight. Obesity is characterized by an excess of energy‐storing white fat. An ingenious and sought‐after strategy against obesity is to activate energy‐consuming beige fat, which is converted ...
Jiamin Liu, Linjie Ni, Minmin Peng, Yiying Liang, Chan Lu, Hanying Zheng, Zicheng Huang, Jinde Zhang, Ronghe Chen   +8 more
doaj   +1 more source

Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.

PLoS Biology, 2017
Enhancing brown fat activity and promoting white fat browning are attractive therapeutic strategies for treating obesity and associated metabolic disorders.
Zhiqiang Bai, Xiao-Ran Chai, Myeong Jin Yoon, Hye-Jin Kim, Kinyui Alice Lo, Zhi-Chun Zhang, Dan Xu, Diana Teh Chee Siang, Arcinas Camille Esther Walet, Shao-Hai Xu, Sook-Yoong Chia, Peng Chen, Hongyuan Yang, Sujoy Ghosh, Lei Sun   +14 more
doaj   +1 more source

Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge

Biology of Sex Differences, 2019
Background The obesity-related risk of developing metabolic syndrome is higher in males than in females of reproductive age, likely due to estrogen-mediated reduced adipose tissue inflammation and fibrosis with hypertrophied adipocytes.
Sujoy Ghosh, Jessica L. Taylor, Tamra M. Mendoza, Thanh Dang, David H. Burk, Yongmei Yu, Gail Kilroy, Z. Elizabeth Floyd   +7 more
doaj   +1 more source

Brown and Beige Fat: Therapeutic Potential in Obesity

Indonesian Biomedical Journal, 2014
BACKGROUND: The epidemic of obesity and type 2 diabetes presents a serious challenge to scientific and biomedical communities worldwide. There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the ...
Anna Meiliana, Andi Wijaya
doaj   +1 more source

Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis [PDF]

, 2023
Grace Park, John D. Haley, Johnny Le, Su Myung Jung, Timothy P. Fitzgibbons, Ekaterina Korobkina, Huawei Li, Shelagh M. Fluharty, Qingbo Chen, Jessica B. Spinelli, Chinmay M. Trivedi, Cholsoon Jang, David A. Guertin   +12 more
openalex   +1 more source

Effect of Chronic Athletic Activity on Brown Fat in Young Women

PLoS ONE, 2016
Background The effect of chronic exercise activity on brown adipose tissue (BAT) is not clear, with some studies showing positive and others showing negative associations.
V. Singhal, G. D. Maffazioli, Kathryn E. Ackerman, Hang Lee, Elisa F. Elia, Ryan Woolley, G. Kolodny, A. Cypess, M. Misra   +8 more
semanticscholar   +1 more source