Results 61 to 70 of about 4,349,521 (358)

Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas [PDF]

open access: yes, 2017
Tumor-associated macrophages (TAMs) are major constituents of the tumor microenvironment in solid tumors and have been implicated as mediators of tumor progression, invasion and metastasis.
Adhikari, Smita   +7 more
core   +2 more sources

Pathologic Fracture of the Femur in Brown Tumor Induced in Parathyroid Carcinoma: A Case Report

open access: yesHip & Pelvis, 2016
Brown tumor refers to a change of skeletones that develops as a complication of hyperparathyroidism. As osteoclast is activated to stimulate reabsorption and fibrosis of bone, it causes a cystic change of the bone. Parathyroid carcinoma is being reported
Sanghwa Park   +3 more
semanticscholar   +1 more source

Tumor pardo en la sínfisis mandibular como primera manifestación clínica de hiperparatiroidismo: diagnóstico y tratamiento [PDF]

open access: yes, 2005
El tumor pardo es una de las lesiones óseas que pueden encontrarse en pacientes con hiperparatiroidismo. Pueden localizarse en cualquier hueso, afectando ocasionalmente al territorio craneo- maxilofacial.
Antón Badiola, I.   +2 more
core   +1 more source

Brown tumor of the jaw after pregnancy and lactation in a MEN1 patient

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2016
Summary Skeletal manifestations of primary hyperparathyroidism (pHPT) include brown tumors (BT), which are osteoclastic focal lesions often localized in the jaws. Brown tumors are a rare manifestation of pHTP in Europe and USA; however, they are frequent
A. Casteràs   +6 more
semanticscholar   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Epigenetic aberrations and cancer [PDF]

open access: yes, 2006
The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms.
Brown, Mark A., Ducasse, Miryam
core   +3 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Evaluation of Hepatocellular Carcinoma Transarterial Chemoembolization using Quantitative Analysis of 2D and 3D Real-time Contrast Enhanced Ultrasound. [PDF]

open access: yes, 2018
Quantitative 2D and 3D contrast-enhanced ultrasound (CEUS) was assessed to evaluate early transarterial chemoembolization (TACE) treatment response. Seventeen patients scheduled for TACE for the treatment of hepatocellular carcinoma participated in the ...
Eisenbrey, John R.   +7 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Primary Hyperparathyroidism Presented with Peripheral Brown Tumor in the Oral Cavity: A Case Report

open access: yesMedicine Science, 2014
Brown tumor is a non-neoplastic lesion which resulting from abnormal bone metabolism caused by hyperparathyroidism. We report a rare case of peripheral brown tumor related with primary hyperparathyroidism which simulating a peripheral giant cell ...
Gulsah Elbuken   +8 more
doaj   +1 more source

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