Results 31 to 40 of about 61,041 (305)
A lysozyme-like protein in Brucella abortus is involved in the early stages of intracellular replication [PDF]
Secretion of proteins in Gram-negative bacteria is a high-energy consuming process that requires the translocation across two membranes and a periplasmic space composed of a mesh like layer, the peptidoglycan.
Czibener, Cecilia+2 more
core +1 more source
Key Points Brucella abortus induces a STING-dependent UPR. Bacterial c-di-GMP recognition by STING triggers B. abortus–induced UPR. UPR blockade inhibits B. abortus replication in vitro and in vivo.
Erika S. Guimarães+9 more
semanticscholar +1 more source
RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella [PDF]
Brucellaceae are stealthy pathogens with the ability to survive and replicate in the host in the context of a strong immune response. This capacity relies on several virulence factors that are able to modulate the immune system and in their structural ...
Altabe, Silvia Graciela+10 more
core +1 more source
The Metabolism of Erythritol by Brucella abortus [PDF]
The growth of a virulent strain of Brucella abortus was stimulated by low concentrations of erythritol in a medium containing high concentrations of glucose and a wide range of amino acids. During growth in this medium the organisms used about 1 1/2 times their weight of erythritol as a carbon and energy source.
H. Smith, J. D. Anderson
openaire +3 more sources
Antibiotic persistence of intracellular Brucella abortus
Background Human brucellosis caused by the facultative intracellular pathogen Brucella spp. is an endemic bacterial zoonosis manifesting as acute or chronic infections with high morbidity. Treatment typically involves a combination therapy of two antibiotics for several weeks to months, but despite this harsh treatment relapses occur at a rate of 5–15%
Selma Mode+3 more
openaire +5 more sources
To date, the implications of interleukin 6 (IL-6) for immune responses in the context of Brucella infection are still unknown. In the present study, we found that Brucella abortus infection induced marked production of IL-6 in mice that was important for
H. T. Hop+10 more
semanticscholar +1 more source
Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection [PDF]
This paper considers the problem of finding global states incoming to a specified global state in a Boolean network, which may be useful for pre-processing of finding a sequence of control actions for a Boolean network and for identifying the basin of ...
Abo-Shehada, M N+4 more
core +4 more sources
La Brucelosis es una enfermedad zoonótica extendida a nivel mundial en el ganado bovino, ocasionada principalmente por Brucella abortus, previamente reportada en ciertas regiones del Ecuador.
Omar Santiago Andrade-Guzmán+6 more
doaj +1 more source
The small protein CydX is required for function of cytochrome bd oxidase in Brucella abortus. [PDF]
A large number of hypothetical genes potentially encoding small proteins of unknown function are annotated in the Brucella abortus genome. Individual deletion of 30 of these genes identified four mutants, in BAB1_0355, BAB2_0726, BAB2_0470, and BAB2_0450
de Jong, Maarten F+5 more
core +3 more sources
Brucella abortus in Milk [PDF]
As a result of the extensive investigations in America and on the Continent into the relationship of Br. abortus to undulant fever in man, attention in this country has been directed to cases of fever due to obscure causes, with the result that an increasing number of cases of undulant fever are being reported.
openaire +3 more sources