Results 41 to 50 of about 1,098,228 (160)

Pilot satellitome analysis of the model plant, Physcomitrella patens, revealed a transcribed and high-copy IGS related tandem repeat [PDF]

Comparative Cytogenetics, 2018
Satellite DNA (satDNA) constitutes a substantial part of eukaryotic genomes. In the last decade, it has been shown that satDNA is not an inert part of the genome and its function extends beyond the nuclear membrane.
Ilya Kirov, Marina Gilyok, Andrey Knyazev, Igor Fesenko   +3 more
doaj   +2 more sources

Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr^−/− Mice

Cells, 2022
Lipid peroxidation from oxidative stress is considered a major contributor to age-related macular degeneration (AMD). The retina is abundant with circulating low-density lipoproteins (LDL), which are taken up by LDL receptor (LDLR) in the RPE and Müller ...
Parameswaran Gangadharan Sreekumar, Feng Su, Christine Spee, Eduardo Araujo, Steven Nusinowitz, Srinivasa T Reddy, Ram Kannan   +6 more
doaj   +1 more source

Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane [PDF]

Journal of Ophthalmology, 2017
A precise evaluation of the retinal nerve fiber layer thickness (RNFLT) is key for diagnosing and monitoring glaucoma. The Bruch’s membrane opening minimum rim width (BMO-MRW) has been proposed as a reproducible assessment of the optic nerve. The BMO-MRW measures the minimum distance from the BMO to the internal limiting membrane.
Robert Kromer, Martin Stephan Spitzer
openaire   +3 more sources

3D ex vivo platform for high‐throughput immunotherapy screening in relapsed/refractory lymphoma patients

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Relapsed/refractory (R/R) B‐cell lymphomas (B‐NHL) remain incurable, with limited predictive biomarkers to guide immunotherapy. Preclinical platforms that faithfully preserve the immune context and the viability of patient samples are critically needed for relevant high‐throughput drug testing.
Fabien Gava, Paul Marcoux, Neus Serrat, Pauline Gravelle, Sonia Quertinmont, Marie Tosolini, Carla Faria, Juan G. Valero, Christina Schniederjohann, Cathy Quelen, Fanny Bouquet, Catia Fonseca, Sylvia Herter, Laura C. Deak, Ron McCord, Eugene Chiang, Peter‐Martin Bruch, Loïc Ysebaert, Patricia Pérez‐Galán, Camille Laurent, Christine Bezombes   +20 more
wiley   +1 more source

Intravitreal bevacizumab (Avastin) in choroidal neovascular membrane in angioid streaks

Indian Journal of Ophthalmology, 2007
Angioid streaks are crack-like dehiscences in the Bruch′s membrane, which predispose to the development of a choroidal neovascular membrane (CNVM) that carries a poor visual outcome.
Sachdev Nishant, Vishwanathan Kavitha, Gupta Vishali, Singh Ramandeep, Gupta Amod   +4 more
doaj  

LES STRIES ANGIOÏDES : A PROPOS DE 10 CAS

Journal de la Société Marocaine d’Ophtalmologie, 2015
Les stries angioïdes correspondent à des lignes de rupture localisées de la membrane de Bruch, habituellement asymptomatiques, ces stries peuvent se néovasculariser et entraîner un syndrome maculaire avec baisse marquée de l’acuité visuelle.
F Alami, N El Berdaoui, A Boulanouar, Z Hajji, A Berraho   +4 more
doaj   +1 more source

Systematic Analysis of Plasma‐Derived Extracellular Vesicle‐Enriched Samples in Age‐Related Macular Degeneration Reveals Oxidative Stress Linked to Altered Lipid and Protein Profiles

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Vision impairment caused by age‐related macular degeneration (AMD) is a global health priority. Retinal pathology is driven by ageing and exacerbated by genetic and environmental risk factors. Peripheral blood circulation is increasingly recognised as a contributor to disease initiation and progression, and a source of biomarkers to support ...
Marzena Kurzawa‐Akanbi, Jennifer Haggarty, Carina Hansohn, Mohamed T. Patel, Angela J. Cree, Peisi Teo, Milly Armstrong, Nathan Coles, Mark Platt, Helen Griffiths, Heather J. Cordell, Ahmad Khundakar, Pola Goldberg Oppenheimer, Phillip Whitfield, Andrew Lotery, Henning Urlaub, Sina Mozaffari‐Jovin, Majlinda Lako   +17 more
wiley   +1 more source

Morphological assessment of lamina cribrosa in idiopathic intracranial hypertension

Indian Journal of Ophthalmology, 2020
Purpose: Technological development of optic coherence tomography has enabled a detailed assessment of the optic nerve and deeper structures and in vivo measurements.
Ipek Tanir Tatar, Banu Solmaz, Zeynep Gizem Erdem, Isıl Pasaoglu, Ali Demircan, Beril Tülü Aygün, Abdullah Ozkaya   +6 more
doaj   +1 more source

Risk factors for the development of subretinal fluid in the fellow eyes of patients with chronic central serous chorioretinopathy

Acta Ophthalmologica, Volume 104, Issue 6, Page 666-673, September 2026.
Abstract Purpose To assess the risk of subretinal fluid (SRF) development in the fellow eye of chronic central serous chorioretinopathy (cCSC) patients with unilateral SRF at baseline. Methods Medical records of 334 presumed cCSC patients were retrospectively reviewed.
Helena M. A. Feenstra, Tahir Cakar, Joost Brinks, Camiel J. F. Boon, Elon H. C. van Dijk   +4 more
wiley   +1 more source

Inner limiting membrane bridges within Bruch’s membrane defects in pathological myopia

Scientific Reports, 2022
The purpose of the study was to examine peculiarities of the inner limiting membrane (ILM) in axially elongated eyes. The histomorphometric study included human globes enucleated due to reasons such as painful secondary angle-closure glaucoma or ...
Songhomitra Panda-Jonas, Jost B. Jonas, Rahul A. Jonas   +2 more
doaj   +1 more source