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Brugada syndrome (BrS) is an "inherited" condition characterized by predisposition to syncope and cardiac arrest, predominantly during sleep. The prevalence is ∼1:2,000, and is more commonly diagnosed in young to middle-aged males, although patient sex does not appear to impact prognosis.
A. D. Krahn+5 more
semanticscholar +3 more sources
Experimental Models of Brugada syndrome [PDF]
Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with sudden cardiac death. It accounts for up to 20% of sudden deaths in patients without structural cardiac abnormalities.
F. Sendfeld+5 more
semanticscholar +6 more sources
Fever as a Catalyst for Life-Threatening Arrhythmias in Brugada Syndrome: A Rare Case of Brugada Syndrome Unmasked in a Young Male. [PDF]
ABSTRACT Brugada syndrome (BrS) is a rare, genetically predisposed arrhythmic disorder associated with an elevated risk of sudden cardiac death (SCD) due to ventricular arrhythmias. Fever is a recognized trigger that can unmask the Type 1 Brugada electrocardiogram (ECG) pattern and precipitate life‐threatening arrhythmias, even in individuals without ...
Khalil I, Hossain MI.
europepmc +2 more sources
A novel clinical entity characterized by ST segment elevation in right precordial leads (V1 to V3), incomplete or complete right bundle branch block, and susceptibility to ventricular tachyarrhythmia and sudden cardiac death has been described by Brugada et al. in 1992. This disease is now frequently called "Brugada syndrome" (BrS).
Napolitano C, PRIORI, SILVIA GIULIANA
openaire +7 more sources
The Brugada syndrome is a genetic disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death.1 it is named by the Spanish cardiologists Pedro Brugada and Joseph Brugada.
Syed Azhar Sherazi, Muhammad Rehan Khan
doaj +2 more sources
Clinical Features of Brugada Syndrome Patients With SCN5A Variants. [PDF]
Longer r‐J interval in lead V1, fragmented QRS and carrying SCN5A variants other than benign variants are independently associated with the cardiac events in BrS patients. LAS40 and RMS40 are useful for the risk stratification in BrS patients with SCN5A VUS or pathogenic variants.
Okamura S+13 more
europepmc +2 more sources
Sumatriptan Induced Brugada Syndrome, a Rare Presentation of a Commonly Used Drug [PDF]
ABSTRACT We aim to highlight an important and rare association of Brugada Syndrome with a commonly used medication, Sumatriptan, which is used as an aborting Migraine headaches. This life‐threatening condition needs early diagnosis and prompt management with vigilant follow‐up for better patient outcomes.
Iqbal P+7 more
europepmc +2 more sources
Long-term of epicardial radiofrequency ablation and benefit for recurrent ventricular arrhythmia in Brugada syndrome: A systematic review and meta-analysis. [PDF]
Epicardial radiofrequency ablation significantly reduces recurrent ventricular arrhythmias and ICD shocks in Brugada syndrome, with excellent long‐term safety and no reported mortality. Epicardial ablation is an effective strategy for sustained rhythm stabilization. Abstract Background Brugada syndrome (BrS) is a rare cardiac channelopathy linked to an
Adji AS+7 more
europepmc +2 more sources
The Brugada syndrome demonstrates characteristic electrocardiogram features and is a significant cause of sudden death in young adults with overtly normal cardiac structure and function. The genetic basis has not yet been fully elucidated but our understanding of the causative mutations and modifiers of arrhythmic events is advancing rapidly alongside ...
Bastiaenen, Rachel, Behr, Elijah R.
openaire +2 more sources