Results 151 to 160 of about 18,811 (223)

A Highly Conserved SNARE‐Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3426-3440, May 2026.
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk, Peitong Li, Hafiz Muhammad Khalid Abbas, Mst Shamira Sultana, Sarbottam Piya, Nicole Coffey, Cengizhan Öztürk, Sobhan Bahrami Zadegan, Susan Thomas Laird, Mazen Alazem, Samantha P. Nuzzi, J. Hollis Rice, Chris Wyman, Tessa Burch‐Smith, Vince Pantalone, Tarek Hewezi   +15 more
wiley   +1 more source

A combinatorial screening protocol for identifying novel and highly potent dual-target inhibitor of BRD4 and STAT3 for kidney cancer therapy

Frontiers in Pharmacology
Concurrent inhibition of bromodomain-containing protein 4 (BRD4) and signal transductor and activator of transcription 3 (STAT3) could potentially be an effective strategy against renal cell carcinoma (RCC).
Shizhu Zhang, Nan Wu, Yifei Geng, Lixia Guan, Miao-Miao Niu, Jindong Li, Lusha Zhu   +6 more
doaj   +1 more source

Discovery of [1,2,4]triazolo[1,5‐a]pyrimidine‐Imatinib Hybrids With Selective Cytotoxic Activity: A Mechanistically Divergent Series From Direct BCR‐ABL1 Inhibition

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Discovery of imatinib–triazolopyrimidine hybrids with selective cytotoxicity and a mechanism distinct from classical BCR‐ABL1 inhibition. This bioisosteric strategy introduces a novel compounds, paving the way for innovative antileukemic therapies with differentiated profiles.
Stefany Castro Bazan Moura, Andressa Paula de Oliveira, Joao de Mello Rezende Neto, Rafael Ferreira Dantas, Floriano Paes Silva‐Jr, Luiz Claudio Pimentel, Mayara Salles do Nascimento Carvalho, Debora Inacio Leite, Daiane Vitoria da Silva, Monica Macedo Bastos, Nubia Boechat   +10 more
wiley   +1 more source

HM1.24/BST-2 is constitutively poly-ubiquitinated at the N-terminal amino acid in the cytoplasmic domain. [PDF]

Biochem Biophys Rep, 2020
Fujimoto K, Nakashima S, Uchida S, Amen RNS, Ishii Y, Hirota Y, Tanaka Y.   +6 more
europepmc   +1 more source

The Nef Protein of the Macrophage Tropic HIV-1 Strain AD8 Counteracts Human BST-2/Tetherin. [PDF]

Viruses, 2020
Giese S, Lawrence SP, Mazzon M, Nijmeijer BM, Marsh M.   +4 more
europepmc   +1 more source

CROPS AND LIVESTOCK BUDGETS ESTIMATES FOR MICHIGAN [PDF]

Agricultural Finance,
Dartt, Barbara, Schwab, Gerald
core   +1 more source

Lymphocyte-specific protein 1 (LSP1) regulates bone marrow stromal cell antigen 2 (BST-2)-mediated intracellular trafficking of HIV-1 in dendritic cells. [PDF]

FEBS Lett, 2020
Kulkarni R, Jiang S, Birrane G, Prasad A.   +3 more
europepmc   +1 more source

Narrow-band analysis of nonstationary processes. [PDF]

The behavior of averaged periodograms and cross-periodograms of a broad class of nonstationary processes is studied. The processes include nonstationary ones that are fractional of any order, as well as asymptotically stationary fractional ones.
Marinucci, D., Robinson, Peter M.
core   +1 more source

Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs. [PDF]

J Virol, 2020
Yao W, Yoshida T, Hashimoto S, Takeuchi H, Strebel K, Yamaoka S.   +5 more
europepmc   +1 more source

Arf GTPases Define BST-2-Independent Pathways for HIV-1 Assembly and Release. [PDF]

Viruses
Smith A, Dotson D, Sutton J, Xie H, Dong X.   +4 more
europepmc   +1 more source