Results 11 to 20 of about 32,229 (219)
How Sodium and Calcium Ions Pass Through Batrachotoxin-Bound Sodium Channel [PDF]
ToxinsSteroidal sodium channel agonist batrachotoxin (BTX), one of the most potent animal toxins, dramatically increases calcium permeation and alters other channel characteristics.
Boris S. Zhorov
doaj +2 more sources
The Comparative Effectiveness of Botulinum Toxin-A Injection Therapy Versus Augmentation Uretero-Enterocystoplasty for the Treatment of Lower Urinary Tract Dysfunction [PDF]
International Neurourology Journal, 2023 Purpose We investigated the effectiveness of intravesical botulinum toxin-A (BTX-A) injection therapy in patients with lower urinary tract dysfunction (LUTD) and upper urinary tract (UUT) deterioration and evaluated whether BTX-A injection therapy could ...
Xuesheng Wang, Zhonghan Zhou, Limin Liao
doaj +1 more source
Counting Process Based Dimension Reduction Methods for Censored Outcomes [PDF]
, 2018 We propose a class of dimension reduction methods for right censored survival data using a counting process representation of the failure process. Semiparametric estimating equations are constructed to estimate the dimension reduction subspace for the ...
Sun, Qiang +3 more
core +3 more sources
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
, 2015 Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa +6 more
core +2 more sources
Cell & Bioscience, 2020 Background Botulinum toxin type A (BTX-A) was considered to be a new potential drug for neuropathic pain (NP) treatment. Results In vivo, BTX-A attenuated chronic compression injury (CCI)-induced pain in rats, and reduced production of pro-inflammatory ...
Xuan Wang +7 more
doaj +1 more source
Effect of Botulinum Toxin A on Bladder Pain—Molecular Evidence and Animal Studies
Toxins, 2020 Botulinum toxin A (BTX-A) is a powerful neurotoxin with long-lasting activity that blocks muscle contractions. In addition to effects on neuromuscular junctions, BTX-A also plays a role in sensory feedback loops, suggesting the potentiality for pain ...
Ting-Chun Yeh +3 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2017 Background Botulinum toxin A (BTX-A) has been used to reduce spasticity in children with cerebral palsy (CP) for decades. The purpose of this study was to analyze to what extent BTX-A treatment was used to treat spasticity in a total population of ...
Maria Franzén +2 more
doaj +1 more source
Differential Contribution of Subunit Interfaces to α 9 α 10 Nicotinic Acetylcholine Receptor Function [PDF]
, 2017 Nicotinic acetylcholine receptors can be assembled from either homomeric or heteromeric pentameric subunit combinations. At the interface of the extracellular domains of adjacent subunits lies the acetylcholine binding site, composed of a principal ...
Boffi, Juan Carlos +11 more
core +3 more sources
Renal Failure, 2019 The aim of this work was to evaluate the efficacy and safety of botulinum toxin A (BTX-A) treatment in patients with neurogenic detrusor overactivity.
Shang-Jun Wu +6 more
doaj +1 more source
Libyan Journal of Medicine, 2019 Stroke is the second leading cause of mortality worldwide and one of the main causes of adult disability. Many studies have suggested that combination therapies provide better outcomes in patients with stroke than monotherapies.
Mohammad Nasb +4 more
doaj +1 more source