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In Vivo Model of Short-Term Efficacy and Favorable Safety of Botulinum Toxin Type E Compared with Type A [PDF]

Toxins
Botulinum toxin suppresses neurotransmitter release, thereby inhibiting muscle contraction and inducing flaccid paralysis. Botulinum toxin type A (BoNT/A) is widely used for neuromuscular blockade but, upon repeated administration, may cause long-lasting
Jeong-Sun Nam, Daewon Yoon, Yujin Kim, Su-Young Kim, Jae-Young Kim, Yoonkyoung Cha, Joon Seok, Beom Joon Kim   +7 more
doaj   +2 more sources

Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research [PDF]

Toxins
Pediatric torticollis, predominantly resulting from congenital muscular torticollis, is characterized by unilateral shortening of the sternocleidomastoid muscle, leading to head tilt and limited cervical mobility.
Na-Yoen Kwon, Soo-Hyun Sung, Hyun-Kyung Sung   +2 more
doaj   +2 more sources

Iatrogenic botulinum Toxin Type A poisoning with persistent unilateral vocal cord paralysis: a case report and clinical implications [PDF]

Frontiers in Pharmacology
With the continuous advancement of medical aesthetic technologies, botulinum toxin injection has emerged as a prevalent method for wrinkle removal and facial enhancement. However, improper administration can result in botulism incidents.
Shizhao Xiang, Yu Du, Yu Du
doaj   +2 more sources

Botulinum toxin preparations: areas for improvement and issues of standardisation

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Botulinum toxin preparations are a good example of using a deadly toxin as a unique therapeutic agent. However, there are many unresolved issues related to biotechnology, biological activity, interchangeability, and standardisation ...
M. V. Savkina, M. A. Krivykh, L. V. Sayapina, Yu. I. Obukhov, V. P. Bondarev   +4 more
doaj   +1 more source

Prolonged Antipruritic Effect of Botulinum Toxin Type A on Cowhage-induced Itch: A Randomized, Single-blind, Placebo-controlled Trial

Acta Dermato-Venereologica, 2023
Botulinum toxin type A (Botox®) is thought to have antipruritic effects through inhibition of pruritic factors, including acetylcholine, substance P, and glutamate. The aim of this randomized, single-blind, placebo-controlled trial was to test the effect
Leigh A. Nattkemper, Ashley Vander Does, Carolyn M. Stull, Michael J. Lavery, Rodrigo Valdes-Rodriguez, Marlene McGregory, Yiong Huak Chan, Gil Yosipovitch   +7 more
doaj   +1 more source

Efficacy of botulinum toxin type B (rimabotulinumtoxinB) in patients with cervical dystonia previously treated with botulinum toxin type A: A post-marketing observational study in Japan

eNeurologicalSci, 2021
To date, efficacy data on botulinum toxin type B (rimabotulinumtoxinB) in patients with cervical dystonia (CD) previously treated with botulinum toxin type A in a large population are lacking; thus, we aimed to evaluate type B efficacy in this patient ...
Ryuji Kaji, Akira Endo, Michiko Sugawara, Mika Ishii   +3 more
doaj   +1 more source

Isolation and typing of Clostridium botulinum from milk powder of an enterprise associated with a case of infant botulism

Zhongguo shipin weisheng zazhi, 2023
ObjectiveThe aim of this study was to detect botulinum toxin and Clostridium botulinum （C.botulinum） in 30 batches of infant formula milk powder obtained from an enterprise and to analyze the whole genome of the strain of C.
LUO Haipeng, QU Hongren, DING Bo, REN Xiu, ZHAO Linna, BAI Jichao, WANG Yaping, LIN Lan, CUI Shenghui   +8 more
doaj   +1 more source

Botulinum toxin type A in treatment of chronic migraine, spasticity and bruxism

Journal of Education, Health and Sport, 2023
Introduction: Nowadays, botulinum toxin has found use in many disease entities such as chronic migraine, spasticity, bruxism and many others. Among serotypes A-E, type A is mainly used in treatment.
Klaudia Kuliga, Katarzyna Dobko, Gabriela Frącz, Agata Glac, Kinga Musz, Natalia Sejnowska, Agnieszka Socha, Agata Surowiec, Kinga Śnieżek, Anna Zając   +9 more
doaj   +1 more source

An Update on the Cosmetic Use of Botulinum Toxin: The Pattern of Practice among Korean Dermatologists

Toxins, 2022
The efficacy and safety of botulinum toxin injection have made it a popular aesthetic procedure worldwide. A cross-sectional survey was performed in order to determine the pattern of type A botulinum toxin injections in cosmetic practice, for which an 18-
Nark-Kyoung Rho, Kwang-Ho Han, Hei-Sung Kim   +2 more
doaj   +1 more source

Botulinum toxin type A injections for treatment of chronic anal fissures

Амбулаторная хирургия, 2021
An anal fissure is one of the most common diseases of the anal canal with the incident rate of 20–23 cases per 1000 citizens. Most of acute anal fissures are healed spontaneously but a few of them can become chronic process.
M. V. Abritsova, N. R. Torchua
doaj   +1 more source