Results 1 to 10 of about 21,819 (222)
Probing the properties of PTEN specific botulinum toxin type E mutants [PDF]
Journal of Neural TransmissionAbstract Botulinum neurotoxins (BoNT) are established biopharmaceuticals for neuromuscular and secretory conditions based on their ability to block neurotransmitter release from neurons by proteolyzing specific soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins.
Schiavone, Giorgia +8 more
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Thermal Inactivation of Type E Botulinum Toxin [PDF]
Applied Microbiology, 1967 The theoretical required cooking times for inactivation of type E Clostridium botulinum toxin (5,000 ld 50 mouse units per 0.5 ml) in haddock fillets of various sizes were calculated by graphical integration of the toxin inactivation
J J, Licciardello +3 more
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Susceptibility of Mink to Clostridium Botulinum Type E Toxin [PDF]
Acta Veterinaria Scandinavica, 1969 Experiments aiming at elucidation of the toxicity of Clostridium botulinum type E for mink are described. The observations indicate that amounts in the order of 2 x10s intraperitoneal MLD (mice) or approximately 200 MLD per g of type E toxin will kill a mink after oral administration.
A, Skulberg, M, Valland
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Susceptibility of Foxes to Clostridium Botulinum Type C and E Toxins [PDF]
Acta Veterinaria Scandinavica, 1977 Investigations were performed to determine the exact susceptibility of foxes to Clostridium botulinum type C and E toxins. Doses of 5 mill. MLD type C toxin mixed with the feed did not cause symptoms of botulism in either cubs or adult foxes. Subcutaneous injections of 300,100(0 MLD or more were fatal to cubs, while 750,000 MLD caused the death of all ...
M, Yndestad +2 more
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ACTIVATION PHENOMENON OF CLOSTRIDIUM BOTULINUM TYPE E TOXIN [PDF]
Journal of Bacteriology, 1962 Gerwing, Julia (The University of British Columbia, Vancouver, Canada), Claude E. Dolman, and David A. Arnott . Activation phenomenon of Clostridium botulinum type E toxin. J. Bacteriol. 84: 302–306.
J, GERWING, C E, DOLMAN, D A, ARNOTT
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Comparison of toxins of Clostridium butyricum and Clostridium botulinum type E [PDF]
Infection and Immunity, 1988 The toxin of Clostridium butyricum strains isolated from two infants with botulism is neutralized by antitoxin for type E botulinum toxin. This toxin and that of a C. botulinum type E strain were purified by the same protocol. Both toxins were Mr 145,000 proteins which, when activated with trypsin, were composed of an H subunit of Mr 105,000 and an L ...
J A, Giménez, H, Sugiyama
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Simplified purification method for Clostridium botulinum type E toxin [PDF]
Applied and Environmental Microbiology, 1987 Clostridium botulinum type E toxin was purified in three chromatography steps. Toxin extracted from cells was concentrated by precipitation and dissolving in a small volume of citrate buffer. When the extract was chromatographed on DEAE-Sephadex without RNase or protamine treatment, the first protein peak had most of the toxin but little nucleic acid ...
J A, Giménez, H, Sugiyama
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Kinetics of the Thermal Inactivation of Type E Clostridium botulinum Toxin [PDF]
Applied Microbiology, 1967 Rate of inactivation curves for the “free” toxin, prototoxin, or activated toxin in crude filtrates of Clostridium botulinum type E were nonlinear, consisting of a fast inactivating rate followed by a slow inactivating rate.
J J, Licciardello +3 more
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Growth and Toxin Production of Clostridium botulinum Type E in Milk
Journal of Dairy Science, 1970 Abstract Recently there has been interest in pasteurizing milk products at temperatures as high as 150C. When precautions are taken to avoid recontaminations, the product may have a shelf life of 6 months under refrigeration. Growth and toxin production of six strains of Clostridium botulinum type E in milk were studied with storage at 4.4 7.2, 10 ...
R B, Read, J G, Bradshaw, D W, Francis
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Significance of 12 S Toxin of Clostridium botulinum Type E [PDF]
Journal of Bacteriology, 1969 The pathogenesis of type E botulism is discussed as an aspect of the physicochemical and biological properties of 12 S toxins (prototoxin and trypsin-activated 12 S toxin) and the Eα and Eβ components of each 12 S toxin. A molecular weight of 350,000 was determined for
M, Kitamura, S, Sakaguchi, G, Sakaguchi
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