Results 31 to 40 of about 1,569,840 (207)
Aerosil in Solid-state Buccal Film for Improved and Sustained Delivery of Valsartan: Molecular Docking Studies [PDF]
Chemical and Biochemical Engineering Quarterly, 2023 To overcome low oral bioavailability and short biological half-life, improved and sustained buccal delivery of valsartan has been proposed. Valsartan film with colloidal silicon dioxide has been prepared using HPMC as mucoadhesive polymer matrix by ...
R. Swain +5 more
doaj +1 more source
Pharmaceutics, 2021 The buccal mucosa provides an alternative route of drug delivery that can be more beneficial compared to other administration routes. Although numerous studies and reviews have been published on buccal drug delivery, an extensive review of the ...
Apipa Wanasathop +3 more
doaj +1 more source
Microenvironmental pH Modification in Buccal/Sublingual Dosage Forms for Systemic Drug Delivery
Pharmaceutics, 2023 Many drug candidates are poorly water-soluble. Microenvironmental pH (pHM) modification in buccal/sublingual dosage forms has attracted increasing interest as a promising pharmaceutical strategy to enhance the oral mucosal absorption of drugs with pH ...
Shaolong He, H. Mu
semanticscholar +1 more source
A microneedle platform for buccal macromolecule delivery
Science Advances, 2021 Microneedles with high drug-loaded tips allow fast and painless delivery of biologics into the buccal mucosa.
Ester Caffarel-Salvador +32 more
openaire +3 more sources
Pharmaceutics, 2022 The topical use of imiquimod (IMQ), a non-specific immune response modifier, showed to be a promising therapeutic option for the early-stage treatment of some type of oral cancer, even when performed with a formulation (Aldara®) developed and approved ...
Paula de Freitas Rosa Remiro +9 more
doaj +1 more source
International Journal of Pharmaceutical Investigation, 2021 Objectives: Aim of the present research work is to prepared fast mouth dissolving film of frovatriptan succinate monoydrate. Methods: Fast dissolving buccal film is prepared by Solvent casting method, hydroxypropyl methylcellulose E3 and E15 are helpful ...
P. Bhatt +3 more
semanticscholar +1 more source
Pharmaceutics, 2023 The prevalence of type 2 diabetes (T2D) has been growing worldwide; hence, safe and effective antidiabetics are critically warranted. Recently, imeglimin, a novel tetrahydrotriazene compound, has been approved for use in T2D patients in Japan.
Ali A. Alamer +7 more
doaj +1 more source
Drug Delivery and Translational Research, 2023 Cannabidiol (CBD) has been recognized for its numerous therapeutic benefits, such as neuroprotection, anti-inflammatory effects, and cardioprotection.
Sadikalmahdi Abdella +5 more
semanticscholar +1 more source
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers [PDF]
BioImpacts, 2023 Introduction: Medications used to treat oral ulcers include corticosteroids, anesthetics, and antihistamines. These can be used as gels, mouthwashes, pastes, ointments, etc.
Azadeh Vaezi Moghaddam +4 more
doaj +1 more source
Buccal Drug Delivery of Pravastatin Sodium [PDF]
AAPS PharmSciTech, 2010 The purpose of this study was to develop and optimize formulations of mucoadhesive bilayered buccal tablets of pravastatin sodium using carrageenan gum as the base matrix. The tablets were prepared by direct compression method. Polyvinyl pyrrolidone (PVP) K 30, Pluronic(R) F 127, and magnesium oxide were used to improve tablet properties.
Supriya Shidhaye +3 more
openaire +3 more sources