Aspirin loaded xerogels for buccal and oral GIT delivery for patients with dysphagia to target deep vein thrombosis [PDF]
This study aimed to develop xerogels for delivery of aspirin via the oral (buccal mucosa and GIT) route in geriatric patients with dysphagia. Xerogels were prepared using low molecular weight chitosan (CS), carrageenan (CAR) and metolose (MET) in ...
Smirna Farias
doaj +3 more sources
BUCCAL DRUG DELIVERY: A TECHNICAL APPROACH [PDF]
Over the last few years Pharmaceutical scientists are trying to explore transdermal and transmucosal routes as an alternative to injections. Buccal delivery of the desired drug using mucoadhesive polymers has been the subject of interest since the early 1980s.
Arunkumar Selvi+4 more
openaire +4 more sources
Phospholipid Deformable Vesicles for Buccal Delivery of Insulin.
To investigate the possibility of the enhancing effect of deformable vesicles on buccal delivery of insulin, two kinds of vesicles with and without the presence of sodium deoxycholate (deformable vesicles and conventional vesicles) were prepared by reverse phase evaporation methods.
Xue-Ying Yan+3 more
openaire +5 more sources
Lyophilized wafers comprising carrageenan and pluronic acid for buccal drug delivery using model soluble and insoluble drugs [PDF]
Lyophilized muco-adhesive wafers with optimum drug loading for potential buccal delivery have been developed. A freeze-annealing cycle was used to obtain optimized wafers from aqueous gels containing 2% κ-carrageenan (CAR 911), 4% pluronic acid (F127), 4.
Babur Chowdhry+31 more
core +3 more sources
Bioavailability Enhancement and Formulation Technologies of Oral Mucosal Dosage Forms: A Review [PDF]
The oral mucosa is a versatile surface for drug administration, supporting both local and systemic therapies. Many active substances are effectively absorbed in the oral cavity, offering an alternative to enteral administration by bypassing the harsh ...
Ildikó Bácskay+10 more
doaj +2 more sources
Development and Optimization of Chitosan-Ascorbate-Based Mucoadhesive Films for Buccal Delivery of Captopril. [PDF]
Pamlényi K+7 more
europepmc +2 more sources
The buccal mucosa provides an alternative route of drug delivery that can be more beneficial compared to other administration routes. Although numerous studies and reviews have been published on buccal drug delivery, an extensive review of the ...
Apipa Wanasathop+3 more
doaj +1 more source
Self-Reported Effectiveness and Safety of Trokie® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts. [PDF]
Crowley K, de Vries ST, Moreno-Sanz G.
europepmc +3 more sources
Ibuprofen-Loaded, Nanocellulose-Based Buccal Films: The Development and Evaluation of Promising Drug Delivery Systems for Special Populations. [PDF]
Bolko Seljak K+3 more
europepmc +2 more sources
Microenvironmental pH Modification in Buccal/Sublingual Dosage Forms for Systemic Drug Delivery
Many drug candidates are poorly water-soluble. Microenvironmental pH (pHM) modification in buccal/sublingual dosage forms has attracted increasing interest as a promising pharmaceutical strategy to enhance the oral mucosal absorption of drugs with pH ...
Shaolong He, H. Mu
semanticscholar +1 more source