Results 41 to 50 of about 15,112 (249)
Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery
Membranes, 2022 Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to
Viviana De Caro +3 more
doaj +1 more source
Advanced Intelligent Systems, EarlyView.This study introduces an AI‐guided strategy to design 3D‐printed PEEK implants functionalized with a tryptophan‐enriched alginate hydrogel (TRYALPEEK). The modification improves hydrophilicity, reduces surface roughness, enhances cytocompatibility, and optimizes stress distribution. The platform offers a promising route for personalized implant design,
Wafa Benaatou +8 more
wiley +1 more source
A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery
Nature Communications, 2021 Administration of drugs via the buccal route has attracted much attention in recent years. However, developing systems with satisfactory adhesion under wet conditions and adequate drug bioavailability still remains a challenge.
Shanshan Hu +9 more
doaj +1 more source
Annals of Neurology, EarlyView.We report the first human use of intranasal seletracetam (SEL) to prevent reflex seizures. A patient with epilepsy with reading‐induced seizures on levetiracetam (3,000 mg/day) continued to experience reading‐induced focal seizures with preserved consciousness.
Matthias J. Koepp +9 more
wiley +1 more source
Development of Multilayer Ciprofloxacin Hydrochloride Electrospun Patches for Buccal Drug Delivery [PDF]
, 2022 Jorge Teno +4 more
openalex +1 more source
Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola
The Anatomical Record, EarlyView.Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum +3 more
wiley +1 more source
Applying design of experiments (DoE) on the properties of buccal film for nicotine delivery [PDF]
, 2021 Jirapornchai Suksaeree +6 more
openalex +1 more source
The Anatomical Record, EarlyView.Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Actinopterygii is a major extant vertebrate group, but limited data are available for its earliest members. Here we investigate the morphology of Devonian actinopterygians, focusing on the lower jaw. We use X‐ray computed tomography (XCT) to provide comprehensive descriptions of the mandibles of 19 species, which span the whole of the Devonian
Ben Igielman +11 more
wiley +1 more source
The Anatomical Record, EarlyView.A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman +4 more
wiley +1 more source