Results 41 to 50 of about 1,579,676 (377)

Development of Imeglimin Electrospun Nanofibers as a Potential Buccal Antidiabetic Therapeutic Approach

Pharmaceutics, 2023
The prevalence of type 2 diabetes (T2D) has been growing worldwide; hence, safe and effective antidiabetics are critically warranted. Recently, imeglimin, a novel tetrahydrotriazene compound, has been approved for use in T2D patients in Japan.
Ali A. Alamer, Nasser B. Alsaleh, Alhassan H. Aodah, Abdullah A. Alshehri, Fahad A. Almughem, Sarah H. Alqahtani, Haya A. Alfassam, Essam A. Tawfik   +7 more
doaj   +1 more source

An Alternative Device for the Topical Treatment of Oral Cancer: Development and Ex-Vivo Evaluation of Imiquimod-Loaded Polysaccharides Formulations

Pharmaceutics, 2022
The topical use of imiquimod (IMQ), a non-specific immune response modifier, showed to be a promising therapeutic option for the early-stage treatment of some type of oral cancer, even when performed with a formulation (Aldara®) developed and approved ...
Paula de Freitas Rosa Remiro, Mariana Harue Taniguchi Nagahara, Martina Ghezzi, Alessia Filippini, Anna Demurtas, Silvia Pescina, Patrizia Santi, Cristina Padula, Ângela Maria Moraes, Sara Nicoli   +9 more
doaj   +1 more source

Combining the potential of 3D printed buccal films and nanostructured lipid carriers for personalised cannabidiol delivery

Drug Delivery and Translational Research, 2023
Cannabidiol (CBD) has been recognized for its numerous therapeutic benefits, such as neuroprotection, anti-inflammatory effects, and cardioprotection.
Sadikalmahdi Abdella, Sangseo Kim, Franklin Afinjuomo, Yunmei Song, Richard Upton, Sanjay Garg   +5 more
semanticscholar   +1 more source

The use of a non-absorbable membrane as an occlusive barrier for alveolar ridge preservation: A one year follow-up prospective cohort study [PDF]

, 2020
The aims of this study were to obtain preliminary data and test the clinical efficacy of a novel nonporous dense-polytetrafluoroethylene (d-PTFE) membrane (permamem®, botiss) in alveolar ridge preservation (ARP) procedures with a flapless approach.
D'addona, A., Di Murro, B., Papi, P., Passarelli, P. C., Pompa, G., Tromba, M.   +5 more
core   +1 more source

Buccal Drug Delivery of Pravastatin Sodium [PDF]

AAPS PharmSciTech, 2010
The purpose of this study was to develop and optimize formulations of mucoadhesive bilayered buccal tablets of pravastatin sodium using carrageenan gum as the base matrix. The tablets were prepared by direct compression method. Polyvinyl pyrrolidone (PVP) K 30, Pluronic(R) F 127, and magnesium oxide were used to improve tablet properties.
Supriya Shidhaye, Pritesh V. Thakkar, Neha Dand, Vilasrao J. Kadam   +3 more
openaire   +3 more sources

Advances in oral transmucosal drug delivery [PDF]

, 2011
Original article can be found at : http://sciencedirect.com/ Copyright ElsevierThe successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity.
Brown, Marc, Liu, Fang, Patel, Viralkumar F.   +2 more
core   +1 more source

Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers [PDF]

BioImpacts, 2023
Introduction: Medications used to treat oral ulcers include corticosteroids, anesthetics, and antihistamines. These can be used as gels, mouthwashes, pastes, ointments, etc.
Azadeh Vaezi Moghaddam, Seyed Alireza Mortazavi, Farzad Kobarfard, Reza Bafkary, Behzad Darbasizadeh   +4 more
doaj   +1 more source

Oral transmucosal delivery of naratriptan [PDF]

, 2016
Naratriptan (NAR) is currently used as the hydrochloride salt (NAR.HCl) for the treatment of migraine and is available in tablet dosage forms for oral administration.
Lane, ME, Sattar, M
core   +1 more source

Multiple Roles of Chitosan in Mucosal Drug Delivery: An Updated Review

Marine Drugs, 2022
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after cellulose, is the second biopolymer most abundant in nature, being the primary component of the exoskeleton of crustaceans and insects.
Paola Mura, Francesca Maestrelli, Marzia Cirri, Natascia Mennini   +3 more
doaj   +1 more source

In Vitro and Ex Vivo Evaluation of Penetratin as a Non-invasive Permeation Enhancer in the Penetration of Salmon Calcitonin through TR146 Buccal Cells and Porcine Buccal Tissues

Pharmaceuticals, 2020
Buccal tissues are considered one of the potential alternative delivery route because of fast drug absorption and onset of action due to high vascularization and a non-keratinized epithelial membrane.
Taekwang Keum, Gyubin Noh, Jo-Eun Seo, Santosh Bashyal, Sangkil Lee   +4 more
doaj   +1 more source