Results 41 to 50 of about 1,569,840 (207)

Multiple Roles of Chitosan in Mucosal Drug Delivery: An Updated Review

open access: yesMarine Drugs, 2022
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after cellulose, is the second biopolymer most abundant in nature, being the primary component of the exoskeleton of crustaceans and insects.
Paola Mura   +3 more
doaj   +1 more source

In Vitro and Ex Vivo Evaluation of Penetratin as a Non-invasive Permeation Enhancer in the Penetration of Salmon Calcitonin through TR146 Buccal Cells and Porcine Buccal Tissues

open access: yesPharmaceuticals, 2020
Buccal tissues are considered one of the potential alternative delivery route because of fast drug absorption and onset of action due to high vascularization and a non-keratinized epithelial membrane.
Taekwang Keum   +4 more
doaj   +1 more source

Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration

open access: yesFrontiers in Pharmacology, 2019
The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
doaj   +1 more source

Deformable Nanovesicle-Loaded Gel for Buccal Insulin Delivery

open access: yesPharmaceutics, 2022
Deformable nanovesicles (DNVs) have been widely used in oral mucosal delivery studies of biomolecular drugs. However, their development for oral mucosal preparations has been limited by their physical and chemical instability, the need for small oral ...
Yiyue Guo   +6 more
doaj   +1 more source

Buccal Delivery of Nanoparticles

open access: yes, 2020
The buccal route offers an alternative for drug administration due to its advantages, including the avoidance of the gastrointestinal tract, the hepatic first-pass, enzymatic degradation and chemical instability of certain molecules that would pose a challenge to formulate orally.
Andrea C. Ortiz, Javier O. Morales
openaire   +3 more sources

Novel strategies for the buccal delivery of macromolecules [PDF]

open access: yesDrug Development and Industrial Pharmacy, 2014
For years now, the delivery of small molecules through the buccal mucosal route has been described in the literature, but it has only been over the past decade that investigations into macromolecule delivery via the buccal route have sharply increased.
Morales, Javier O., McConville, Jason T.
openaire   +5 more sources

Buccal drug delivery system

open access: yesInternational Journal of Health Sciences, 2022
The buccal area of the oral mucosa provides an adorable channel of systemic medication distribution within the mouth mucosa. Drugs are delivered via oral mucosal layer, that has a higher first-pass metabolism and degrades gastrointestinal. The medication
R. Dolas   +5 more
semanticscholar   +1 more source

Preparation, Characterization and Evaluation of Guar Films Impregnated with Relaxing Peptide Loaded into Chitosan Microparticles

open access: yesApplied Sciences, 2021
Background: Biological molecules such as therapeutic proteins and peptides have provided ample opportunities for further improvements in health and wellbeing.
Patrícia Batista   +4 more
doaj   +1 more source

Photothermal Activatable Mucoadhesive Fiber Mats for On-Demand Delivery of Insulin via Buccal and Corneal Mucosa.

open access: yesACS Applied Bio Materials, 2022
Electrospun fiber mats loaded with therapeutics have gained considerable attention as a versatile tool in the biomedical field. While these bandages are largely based on fast-dissolving polymers to release the cargo, stimuli-responsive fiber mats have ...
Anna M. Voronova   +13 more
semanticscholar   +1 more source

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