Buccal tissues are considered one of the potential alternative delivery route because of fast drug absorption and onset of action due to high vascularization and a non-keratinized epithelial membrane.
Taekwang Keum+4 more
doaj +1 more source
New insights in gill/buccal rhythm spiking activity and CO2 sensitivity in pre- and post-metamorphic tadpoles (Pelophylax ridibundus) [PDF]
Central CO2chemosensitivity is crucial for all air-breathing vertebrates and raises the question of itsrole in ventilatory rhythmogenesis. In this study, neurograms of ventilatory motor outputs recorded infacial nerve of premetamorphic and postmetamorphic tadpole isolated brainstems, under normo- andhypercapnia, are investigated using Continuous ...
arxiv +1 more source
Deformable Nanovesicle-Loaded Gel for Buccal Insulin Delivery
Deformable nanovesicles (DNVs) have been widely used in oral mucosal delivery studies of biomolecular drugs. However, their development for oral mucosal preparations has been limited by their physical and chemical instability, the need for small oral ...
Yiyue Guo+6 more
doaj +1 more source
MUCOADHESIVE BUCCAL FILMS: A NOVEL APPROACH FOR THE DELIVERY OF ANTI-HYPERTENSIVE DRUGS [PDF]
The buccal drug delivery system is a prominent route of administration for drug delivery through the buccal mucosa. It is rich in blood supply with more surface area for rapid absorption as well as provides direct entry of drugs from the site of ...
GEETA BHAGWAT, YELAVE, ADESH
core +1 more source
Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration
The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
doaj +1 more source
A comparison of vaginal versus buccal misoprostol for cervical ripening in women for labor induction at term (the IMPROVE trial): a triple-masked randomized controlled trial [PDF]
Background Cervical ripening is commonly needed for labor induction. Finding an optimal route of misoprostol dosing for efficacy, safety, and patient satisfaction is important and not well studied for the buccal route.
Bhamidipalli, Surya S.+12 more
core +1 more source
Novel strategies for the buccal delivery of macromolecules [PDF]
For years now, the delivery of small molecules through the buccal mucosal route has been described in the literature, but it has only been over the past decade that investigations into macromolecule delivery via the buccal route have sharply increased.
Morales, Javier O., McConville, Jason T.
openaire +5 more sources
Polysaccharide food matrices for controlling the release, retention and perception of flavours [PDF]
Polysaccharides have many roles across both the food and pharmaceutics industries. They are commonly used to enhance viscosity, stabilise emulsions and to add bulk to food products.
Cook, Sarah L.+3 more
core +1 more source
The buccal area of the oral mucosa provides an adorable channel of systemic medication distribution within the mouth mucosa. Drugs are delivered via oral mucosal layer, that has a higher first-pass metabolism and degrades gastrointestinal. The medication
R. Dolas+5 more
semanticscholar +1 more source
Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed+3 more
core +2 more sources