Results 81 to 90 of about 1,353,755 (237)

Dasatinib and quercetin prevent alveolar bone loss in aged mice

Journal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli, Renata M. Moraes, Yuri C. Santos, Jaqueline L. Ribeiro, Maíra T. Garcia, Renata F. Prado, Florent Elefteriou, Ana Lia Anbinder   +7 more
wiley   +1 more source

DEVELOPMENT AND EVALUATION OF BIOADHESIVE MUCOSAL DOSAGE FORMS OF PILOCARPINE HCL FOR XEROSTOMIA THERAPY

Sabiad
Objective: Saliva maintains vital mouth functions and acts as a barrier to dental health. Xerostomia, which is characterised as a feeling of dry mouth, adversely affects the patient’s quality of life.
Özlem Akbal Dağıstan, Nur Sena Başarır, Sinem Yaprak Karavana, Ayça Yıldız Peköz   +3 more
doaj   +1 more source

Protective factors and critical mucosal thickness for the stability of the peri‐implant soft tissue margin over 5 years: A longitudinal cohort study

Journal of Periodontology, EarlyView.
Abstract Background Peri‐implant soft tissue dehiscence deficiencies (PSTDs) are common esthetic complications in the anterior maxilla, yet the parameters that protect the peri‐implant soft tissue margin (STM) over time remain unclear. Previous studies have identified several risk indicators, but longitudinal thresholds capable of predicting stable STM
Lorenzo Tavelli, Hamoun Sabri, Erfan Barootchi, Martina Stefanini, Giovanni Zucchelli, Hom‐Lay Wang, Istvan A. Urban, Shayan Barootchi   +7 more
wiley   +1 more source

Use of ultrasonography in assessing peri‐implant osseous defects: An in vitro study

Journal of Periodontology, EarlyView.
Abstract Background The purpose of this study is to investigate the feasibility and diagnostic accuracy of ultrasonography in peri‐implant defect identification and evaluation, and to compare ultrasonography (USG) with cone‐beam computed tomography (CBCT) in defect identification and evaluation in an in vitro model.
Melissa Rachel Fok, Alice Yee Ting Kan, Chris Tat Chuen Fok, Ray Tanaka, George Pelekos   +4 more
wiley   +1 more source

Ex Vivo Buccal Permeability of Nanostructured Lipid Carriers (NLCs) Associated with a Peptide Drug Model

Pharmaceutics
Background/Objective: Buccal delivery offers a potential route to circumvent gastrointestinal degradation and hepatic first-pass metabolism, but hydrophilic peptides typically exhibit limited mucosal permeation.
Sebastián Vargas-Valderrama, Javier O. Morales   +1 more
doaj   +1 more source

Aspirin loaded xerogels for buccal and oral GIT delivery for patients with dysphagia to target deep vein thrombosis

British Journal of Pharmacy, 2018
This study aimed to develop xerogels for delivery of aspirin via the oral (buccal mucosa and GIT) route in geriatric patients with dysphagia. Xerogels were prepared using low molecular weight chitosan (CS), carrageenan (CAR) and metolose (MET) in ...
Smirna Farias
doaj   +1 more source

Ultrasound findings associated with neonatal acute liver failure secondary to gestational alloimmune liver disease: A case series

JPGN Reports, EarlyView.
Abstract Objectives Gestational alloimmune liver disease is the leading cause of neonatal acute liver failure, hypothesized to emerge from maternal exposure to an antigen that is expressed on fetal hepatocytes, resulting in maternal‐fetal alloimmune attack and activation of the complement cascade.
Naseem Ravanbakhsh, Ashley M. Upton, Chun‐Sing Huang, Nhu Thao N. Galván, John Goss, Sanjiv Harpavat, Jose A. Hernandez   +6 more
wiley   +1 more source

Best antibiotics for buccal delivery [PDF]

, 2011
Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 64-66).The purpose of the research was to identify the clinical and commercial benefits of switching ...
Goldberg, Manijeh Nazari
core  

Optical Stimulation and Monitoring of the Peripheral Nervous System: Perspectives and Challenges Toward Clinical Translation

Laser &Photonics Reviews, EarlyView.
Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo, Sarassunta Ucci, Anna Aliberti, Patrizio Vaiano, Alessia La Rocca, Francesca Angelone, Silvia Pascarella, Pellegrino Lippiello, Maria Concetta Miniaci, Giuseppe Prisco, Michela Russo, Francesco Amato, Deyanira Contartese, Milena Fini, Gianluca Giavaresi, Lucia Martini, Francesco Rosa, Cosimo Gentile, Emanuele Gruppioni, Armando Ricciardi, Andrea Cusano   +20 more
wiley   +1 more source

Evaluation of Clay-Functionalized Wafers and Films for Nicotine Replacement Therapy via Buccal Mucosa

Pharmaceutics, 2019
The functional physicochemical properties of nicotine (NIC)-loaded composite freeze-dried wafers and solvent-evaporated films comprising hydroxypropylmethylcellulose (HPMC) and sodium alginate (SA), stabilized with magnesium aluminium silicate (MAS ...
Joshua Boateng, Obinna Okeke
doaj   +1 more source