Results 101 to 110 of about 1,353,755 (237)

Development of Thermosensitive and Mucoadhesive Hydrogel for Buccal Delivery of (S)-Ketamine. [PDF]

Pharmaceutics, 2022
Thouvenin A, Toussaint B, Marinovic J, Gilles AL, Dufaÿ Wojcicki A, Boudy V.   +5 more
europepmc   +1 more source

Overdose reversal through peer intervention: Findings from the naloxone prospective outcome research study (NalPORS) on the effectiveness of overdose response by people who use opioids in the United Kingdom and Sweden

Addiction, EarlyView.
Abstract Background/aims Take‐home naloxone (THN) programmes have been introduced in many European countries to provide non‐medically trained people who are likely to witness an opioid overdose, including people who use opioids, with a naloxone kit and training.
Nicola Metrebian, Teodora Dascal, Clare Mackie, Rose Tinch‐Taylor, Ben Carter, Joanne Neale, Mariana Gonzalez Utrilla, Ed Day, Joar Guterstam, Kirsten Horsburgh, Martin Kåberg, Mike Kelleher, Soraya Mayet, Josie Smith, Desiree Eide, Elin Holmén, Rebecca McDonald, Stephen Parkin, Henrik Thiesen, John Strang, NalPORS Research Team, Dean Acreman, Shabana Akhtar, Louise Aitken, Martin Anderson, James Cassidy, Sarah Cosgrove, Jo Grayer, Michelle Hughes, Louise Horn, Anika Miah, John Pratt   +31 more
wiley   +1 more source

Bioavailability Enhancement and Formulation Technologies of Oral Mucosal Dosage Forms: A Review

Pharmaceutics
The oral mucosa is a versatile surface for drug administration, supporting both local and systemic therapies. Many active substances are effectively absorbed in the oral cavity, offering an alternative to enteral administration by bypassing the harsh ...
Ildikó Bácskay, Petra Arany, Pálma Fehér, Liza Józsa, Gábor Vasvári, Dániel Nemes, Ágota Pető, Dóra Kósa, Ádám Haimhoffer, Zoltán Ujhelyi, Dávid Sinka   +10 more
doaj   +1 more source

Vardenafil-Loaded Bilosomal Mucoadhesive Sponge for Buccal Delivery: Optimization, Characterization, and In Vivo Evaluation. [PDF]

Polymers (Basel), 2022
Aldawsari MF, Khafagy ES, Alotaibi HF, Abu Lila AS.   +3 more
europepmc   +1 more source

Artificial Intelligence and Digital Impressions: The Positives and the Pitfalls

Australian Dental Journal, EarlyView.
ABSTRACT Digital impressions are now central to contemporary dental workflows, driven by advances in CAD/CAM manufacturing and intraoral scanning technologies. In parallel, rapid progress in artificial intelligence (AI)—particularly deep learning—has led to its widespread integration into digital impression systems.
Andrew Keeling
wiley   +1 more source

OVERVIEW OF MUCOADHESIVE BIOPOLYMERS FOR BUCCAL DRUG DELIVERY SYSTEMS [PDF]

, 2019
Mucoadhesive dosage forms may be intended for facilitation of prolonged retention time at the application site hence providing drug release in a controlled rate for enhanced improvement of therapeutic activity and its outcome.
SHARMA, AMEYA, RATHORE, NISHANT, SINGH, INDERBIR, MAMAN, PARAMJOT, PURI, VIVEK   +4 more
core   +1 more source

Buccal drug delivery: what’s new and what does the future hold?

, 2014
If low concentrations of drug are required to gain access to the blood, transbuccal drug delivery may be very satisfactory for safe and well-accepted clinical applications.In the coming years, new systems equipped with subsystems able to promote ...
GIANNOLA, Libero Italo, SUTERA, Flavia Maria, DE CARO, Viviana   +2 more
core   +1 more source

Dry emulsions based on alpha cyclodextrin and vegetable oils for buccal delivery of lipophilic drugs

, 2020
Background: Buccal delivery of drugs can be used as an alternative administration route to conventional oral route avoiding the liver first-pass effect and improving patient compliance.
Bigucci F., Abruzzo A., Luppi B., Dalena F., Cerchiara T., Nicoletta F. P., Saladini B.   +6 more
core   +1 more source

Pain and Supplemental Anaesthesia in Mandibular Molar Root Canal Therapy: A Prospective Cohort Analysis of Bone Anatomy and Diagnostic Variables

Australian Endodontic Journal, EarlyView.
ABSTRACT Achieving profound local anaesthesia during mandibular molar root canal treatment can be challenging. This study evaluated procedural pain and supplemental anaesthesia used, considering endodontic diagnosis and buccal bone morphology. Seventy‐seven patients undergoing primary root canal treatment completed a post‐treatment survey questionnaire
Emily Kopec, Rosemary Lindemann, Christopher T. Hogden, Oscar Rysavy, Tabitha Peter, Chandler Pendleton, Fabricio Teixeira, Robert D. Bowers   +7 more
wiley   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source