Results 71 to 80 of about 588,476 (307)

Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease

open access: yesFrontiers in Neuroscience, 2018
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by a progressive movement disorder, psychiatric symptoms, and cognitive impairments.
Swati Naphade   +5 more
doaj   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Modeling and Analysis of Power Processing Systems (MAPPS). Volume 2: Appendices [PDF]

open access: yes
The computer programs and derivations generated in support of the modeling and design optimization program are presented. Programs for the buck regulator, boost regulator, and buck-boost regulator are described.
Carter, R. A.   +5 more
core   +1 more source

A supplement to the moss flora of Paraguay [PDF]

open access: yes, 1998
In “A Preliminary List of the Mosses of Paraguay” Buck (1985) commented on the low level of bryological knowledge in this country. He also pointed out the need for muscological studies and encouraged collectors “to gather bryophytes whenever possible ...
Kuc, Marian
core  

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

open access: yesAdvanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang   +12 more
wiley   +1 more source

Stress analysis due to semen collection using infra-red thermography in rabbits

open access: yesItalian Journal of Animal Science
This research evaluated the thermal response to semen collection in rabbits using infra-red thermography in the eyeball, pinna, and nose, alongside measurements from an infra-red forehead thermometer on the pinna. In the first experiment, 20 rabbits were
D. Serrano-Jara   +4 more
doaj   +1 more source

Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha

open access: yesNeurobiology of Disease, 2016
Loss of parkin E3 ligase activity as a result of parkin gene mutation in rare familial forms of Parkinson's disease (PD) has been shown to be detrimental to mitochondrial function and to contribute to ensuing neurodegeneration.
Almas Siddiqui   +4 more
doaj   +1 more source

A Tax-Based Test of the Dividend Signaling Hypothesis [PDF]

open access: yes
We propose and implement a new test of the dividend signaling hypothesis that is designed to discriminate between dividend signaling and other theories that would account for the apparent existence of a dividend preference.
Adam Wantz, B. Douglas Bernheim
core  

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Comparison of ischemia-directed migration of neural precursor cells after intrastriatal, intraventricular, or intravenous transplantation in the rat

open access: yesNeurobiology of Disease, 2005
Cell replacement therapy may have the potential to promote brain repair and recovery after stroke. To compare how focal cerebral ischemia affects the entry, migration, and phenotypic features of neural precursor cells transplanted by different routes, we
Kunlin Jin   +8 more
doaj   +1 more source

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