Results 1 to 10 of about 352,185 (244)

Chemical Genetics: Budding Yeast as a Platform for Drug Discovery and Mapping of Genetic Pathways

Molecules, 2012
The budding yeast <em>Saccharomyces cerevisiae</em> is a widely used model organism, and yeast genetic methods are powerful tools for discovery of novel functions of genes.
Jorrit Enserink
exaly   +3 more sources

Quantifying the Biophysical Impact of Budding Cell Division on the Spatial Organization of Growing Yeast Colonies

Applied Sciences (Switzerland), 2020
Spatial patterns in microbial colonies are the consequence of cell-division dynamics coupled with cell-cell interactions on a physical media. Agent-based models (ABMs) are a powerful tool for understanding the emergence of large scale structure from ...
Mikahl Banwarth-Kuhn, Suzanne Sindi
exaly   +3 more sources

Design and characterization of allantoin-inducible expression systems in budding yeast [PDF]

Biotechnology for Biofuels and Bioproducts
Background Saccharomyces cerevisiae has been extensively employed as a host for the production of various biochemicals and recombinant proteins. The expression systems employed in S.
Junyi Wang, Jiaxue Ma, Xueyi Luo, Shuo Wang, Xinning Cai, Jifeng Yuan   +5 more
doaj   +2 more sources

Real-Time Monitoring of Dissection Events of Single Budding Yeast in a Microfluidic Cell-Culturing Device Integrated With Electrical Impedance Biosensor

Frontiers in Bioengineering and Biotechnology, 2021
Microfluidic devices in combination with fluorescent microscopy offer high-resolution and high-content platforms to study single-cell morphology, behavior and dynamic process in replicative aging of budding yeast, Saccharomyces cerevisiae.
Zhen Zhu, Yangye Geng, Yingying Wang, Ke Liu, Zhenxiang Yi, Xiangwei Zhao, Shuiping Ouyang, Ke Zheng, Yimin Fan, Zixin Wang   +9 more
doaj   +1 more source

A modeling study of budding yeast colony formation and its relationship to budding pattern and aging. [PDF]

PLoS Computational Biology, 2017
Budding yeast, which undergoes polarized growth during budding and mating, has been a useful model system to study cell polarization. Bud sites are selected differently in haploid and diploid yeast cells: haploid cells bud in an axial manner, while ...
Yanli Wang, Wing-Cheong Lo, Ching-Shan Chou   +2 more
doaj   +1 more source

ESCRT-independent budding of HIV-1 gag virus-like particles from Saccharomyces cerevisiae spheroplasts. [PDF]

PLoS ONE, 2012
Heterologous expression of HIV-1 Gag in a variety of host cells results in its packaging into virus-like particles (VLPs) that are subsequently released into the extracellular milieu.
Andrew P Norgan, Jacqueline R E Lee, Andrea J Oestreich, Johanna A Payne, Eugene W Krueger, David J Katzmann   +5 more
doaj   +1 more source

Mps2 links Csm4 and Mps3 to form a telomere-associated LINC complex in budding yeast

Life Science Alliance, 2020
The canonical LINC complex is composed of two different transmembrane proteins; this work reveals the heterotrimeric composition of the telomere-associated LINC complex in budding yeast. The linker of the nucleoskeleton and cytoskeleton (LINC) complex is
Jinbo Fan, Hui Jin, Bailey A Koch, Hong-Guo Yu   +3 more
doaj   +1 more source

A high-throughput microfluidic diploid yeast long-term culturing (DYLC) chip capable of bud reorientation and concerted daughter dissection for replicative lifespan determination

Journal of Nanobiotechnology, 2022
Background Budding yeast, Saccharomyces cerevisiae, has been extensively favored as a model organism in aging and age-related studies, thanks to versatile microfluidic chips for cell dynamics assay and replicative lifespan (RLS) determination at single ...
Yingying Wang, Zhen Zhu, Ke Liu, Qin Xiao, Yangye Geng, Feng Xu, Shuiping Ouyang, Ke Zheng, Yimin Fan, Nan Jin, Xiangwei Zhao, Mario A. Marchisio, Dejing Pan, Qing-an Huang   +13 more
doaj   +1 more source

Budding yeast in a child with acute leukemia: Nothing CRYPT(O)IC about it

Indian Journal of Pathology and Microbiology, 2022
A 13-year-old girl child with B-cell precursor acute lymphoblastic leukemia presented with complaints of fever, fatigue and left-sided iliac mass of 20 days duration.
Rimjhim Kanaujia, Subramaniam Ramanathan, Rahul Sarode, Rachana Kanaujia, Shivaprakash M Rudramurthy, Swati Gupta   +5 more
doaj   +1 more source

Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2.

PLoS Genetics, 2023
In budding yeast the Rif1 protein is important for protecting nascent DNA at blocked replication forks, but the mechanism has been unclear. Here we show that budding yeast Rif1 must interact with Protein Phosphatase 1 to protect nascent DNA.
Vamsi Krishna Gali, Chandre Monerawela, Yassine Laksir, Shin-Ichiro Hiraga, Anne D Donaldson   +4 more
doaj   +1 more source