Results 71 to 80 of about 58,384 (313)

Grafting biomaterials associated to topical glucocorticoid: effects on pre-osteoblastic cells (MC3T3-E1)

Brazilian Oral Research, 2022
The topical glucocorticoid budesonide has been prescribed before and after sinus lift surgery as adjuvant drug treatment for maxillary sinus membrane inflammation.
Alice de Araújo Ferreira SILVA, Carolina Nemesio de Barros PEREIRA, Danilo Rocha DIAS, Frederico Santos LAGES, Katia Lucy Melo MALTOS, Allyson Nogueira MOREIRA, Elton Gonçalves ZENÓBIO, Ivana Márcia Alves DINIZ   +7 more
doaj   +1 more source

Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]

, 2016
Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz, A. Fink-Wagner, A. Yanez, A. Yorgancioglu, ARIA, C. Baez Loyola, C. Nunes, D. Deleanu, D. Ryan, E. Hossny, F. Braido, F. Lavorini, F. Levi-Schaffer, for Interasma Executive Board, G. Passalacqua, G. Rodrigo, G. Walter Canonica, GA2LEN, H. Saito, I. J. Ansotegui, J. A. Ortega-Martell, J. Berstein, J. Bousquet, J. C. Ivancevich, J. Celedon, K. Dobashi, K. Ohta, L. Caraballo, L. Dubuske, L. J. Rosenwasser, L. P. Boulet, L. Zhang, M. Akdis, M. Ebisawa, M. Sanchez-Borges, M. Tang, M. Zernotti, N. Scichilone, O. S. Usmani, P. Greenberger, P. Vichyanond, R. Mosges, R. Pawankar, S. Benjaponpitak, S. Bonini, S. Fineman, S. N. Gonzalez-Diaz, S. Nakajima, T. Slavyanskaya, T. Zuberbier, W. Burks, Z. Awad El-Sayed   +51 more
core   +14 more sources

A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

ChemMedChem, EarlyView.
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova, Thomas M. Geiger, Lorenzo Cianni, Dominika E. Pieńkowska, Jan Gerhartz, Lina Read, Aleša Bricelj, Alexander Herrmann, Maurice Leon Nelles, Yuen Lam Dora Ng, Marcus D. Hartmann, Jan Krönke, Izidor Sosič, Radosław P. Nowak, Michael Gütschow, Christian Steinebach   +15 more
wiley   +1 more source

Budesonide MMX versus prednisolone in mesalamine-refractory mild to moderate ulcerative colitis: a randomized controlled clinical trial

The Egyptian Journal of Internal Medicine
Background Recently licensed to treat mild or moderate ulcerative colitis (UC), Budesonide MMX is a corticosteroid of the second generation designed to distribute pharmacologically active drugs throughout the colon.
Ashraf M. Osman, Mohammed A. Medhat, Ghada M. Kamal   +2 more
doaj   +1 more source

The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma

Frontiers in Immunology, 2018
Background: Dietary non-digestible galacto-oligosaccharides (GOS) suppress allergic responses in mice sensitized and challenged with house dust mite (HDM).
Kim A. T. Verheijden, Kim A. T. Verheijden, Saskia Braber, Thea Leusink-Muis, Prescilla V. Jeurink, Suzan Thijssen, Aletta D. Kraneveld, Johan Garssen, Johan Garssen, Gert Folkerts, Linette E. M. Willemsen   +10 more
doaj   +1 more source

Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children (Review) [PDF]

, 2009
Background Traditionally inhaled treatment for asthma has been considered as preventer and reliever therapy. The combination of formoterol and budesonide in a single inhaler introduces the possibility of using a single inhaler for both prevention and ...
Adams, Balanzat, Bateman, Berggren, Bisgaard, Bisgaard, Bleecker, Bousquet, Bruce, Buhl, Buhl, Cates, Cates Christopher, D'Urzo, Greenstone, Haahtela, Haahtela, Higgins, Higgins, Ind, Jenkins, Johansson, Jonkers, Kuna, Kuna, Lasserson, Loukides, Lundborg, Ni Chroinin, O'Byrne, O'Byrne, O'Byrne, O'Byrne, O'Byrne, O'Byrne, Palmqvist, Price, Price, Rabe, Rabe, Rabe, Richter, Scicchitano, Sears, Sovani, Tattersfield, Tattersfield, Vogelmeier, Vogelmeier, Vogelmeier, Walters   +50 more
core   +1 more source

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]

, 2018
BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E, Corsello, G, Indinnimeo, L, Miraglia del Giudice, M   +3 more
core   +1 more source

Three-dimensional environment sensitizes pancreatic cancer cells to the anti-proliferative effect of budesonide by reprogramming energy metabolism

Journal of Experimental & Clinical Cancer Research
Background Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer with an aggressive metastatic phenotype and very poor clinical prognosis.
Eduardo Ibello, Federica Saracino, Donatella Delle Cave, Silvia Buonaiuto, Filomena Amoroso, Gennaro Andolfi, Marco Corona, Ombretta Guardiola, Vincenza Colonna, Bruno Sainz Jr, Lucia Altucci, Dario De Cesare, Gilda Cobellis, Enza Lonardo, Eduardo Jorge Patriarca, Cristina D’Aniello, Gabriella Minchiotti   +16 more
doaj   +1 more source

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]

, 2019
Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H, Ge, Moyar Q, Haczku, Angela, Hwang, Jin W, Jiang, Zhilong, Kokalari, Blerina, Redai, Imre G   +6 more
core  

Performance-enhanced mesenchymal stem cells via intracellular delivery of steroids [PDF]

, 2014
Inadequate immunomodulatory potency of mesenchymal stem cells (MSC) may limit their therapeutic efficacy. We report glucocorticoid steroids augment MSC expression and activity of indoleamine-2,3-dioxygenase (IDO), a primary mediator of MSC ...
Ankrum, James A., Dastidar, Riddhi G., Karp, Jeffrey M., Levy, Oren, Ong, Joon Faii   +4 more
core   +2 more sources