Results 81 to 90 of about 38,435 (236)

The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea. [PDF]

, 2019
PurposeDiarrhea is recognized as a common adverse event associated with tyrosine kinase inhibitors (TKIs), with those targeting the ErbB family of receptors being associated with the highest rate of diarrhea.MethodsThis paper reviews data on the ...
Bosserman, Linda, Bryce, Richard, Di Palma, Jack A, Moran, Susan, Olek, Elizabeth, Rugo, Hope S, Tripathy, Debu   +6 more
core  

Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]

, 2016
Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz, A. Fink-Wagner, A. Yanez, A. Yorgancioglu, ARIA, C. Baez Loyola, C. Nunes, D. Deleanu, D. Ryan, E. Hossny, F. Braido, F. Lavorini, F. Levi-Schaffer, for Interasma Executive Board, G. Passalacqua, G. Rodrigo, G. Walter Canonica, GA2LEN, H. Saito, I. J. Ansotegui, J. A. Ortega-Martell, J. Berstein, J. Bousquet, J. C. Ivancevich, J. Celedon, K. Dobashi, K. Ohta, L. Caraballo, L. Dubuske, L. J. Rosenwasser, L. P. Boulet, L. Zhang, M. Akdis, M. Ebisawa, M. Sanchez-Borges, M. Tang, M. Zernotti, N. Scichilone, O. S. Usmani, P. Greenberger, P. Vichyanond, R. Mosges, R. Pawankar, S. Benjaponpitak, S. Bonini, S. Fineman, S. N. Gonzalez-Diaz, S. Nakajima, T. Slavyanskaya, T. Zuberbier, W. Burks, Z. Awad El-Sayed   +51 more
core   +14 more sources

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

Allergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson, Maciej Kupczyk, Barbro Dahlén, Kenji Izuhara, Mina Gaga, Nikos M. Siafakas, Alberto Papi, Bianca Beghe, Guy Joos, Klaus F. Rabe, Elisabeth H. Bel, Sebastian L. Johnston, Pascal Chanez, Mark Gjomarkaj, Peter H. Howarth, Ewa Niżankowska‐Mogilnicka, Roelinde Middelveld, Sven‐Erik Dahlén, Apostolos Bossios, Anna James, on behalf of the BIOAIR (Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease) and ChAMP consortia   +20 more
wiley   +1 more source

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]

, 2018
BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E, Corsello, G, Indinnimeo, L, Miraglia del Giudice, M   +3 more
core   +1 more source

Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of ARIA Experts

Allergy, EarlyView.
We surveyed experts of the ARIA group on the costs of medications for allergic rhinitis in the respective countries. Overall, oral antihistamines are the cheapest medications while fixed combinations of antihistamines + corticosteroids are the most expensive.
Maria Clara Urbano, Rafael José Vieira, Yi‐Kui Xiang, Sara Gil‐Mata, Anna Bedbrook, Baharudin Abdullah, Mona Al‐Ahmad, Maryam Ali Al‐Nesf, Emilio Alvarez‐Cuesta, Salma Mussagy Amade, Julijana Asllani, Kazi S. Bennoor, Elena Camelia Berghea, Mario Calvo‐Gil, Luis R. Caraballo, Elizabeth Castro, Lorenzo Cecchi, Deepa Choudhury, George Christoff, Derek K. Chu, Ieva Cirule, Alvaro A. Cruz, Dejan Dokic, Bilun Gemicioglu, Maria Antonieta Guzman, Ineta Grisle, Tari Haahtela, Elham Hossny, Wolfram Hoetzenecker, Martin Hrubisko, Tomohisa Iinuma, Zhanat Ispayeva, Juan Carlos Ivancevich, Fanny Wai San Ko, Helga Kraxner, Maciej Kupczyk, Violeta Kvedariene, Yen Lam, Désirée E. Larenas‐Linnemann, Bassam Mahboub, Padukudru A. Mahesh, Mohammed Reza Masjedi, Garry McDonald, Amarilis Melendez, Florin Mihaltan, Branislava Milenkovic, Yousser Mohammad, Marek Niedoszytko, Robyn E. O'Hehir, Carmen Panaitescu, Petr Panzner, Nikolaos G. Papadopoulos, José Miguel Fuentes Perez, Nhân Pham‐Thi, Constantinos Pitsios, Davor Plavec, María Susana Repka‐Ramirez, Jan Romantowski, Marylin Valentin Rostan, Menachem Rottem, Hani Salim, Pongsakorn Tantilipikorn, Vesna Tomic‐Spiric, Arunas Valiulis, Leticia de las Vecillas, Maria Teresa Ventura, Dana Wallace, Pascal Werminghaus, Sian Williams, Francisco Javier Plaza Zamora, Ludger Klimek, Torsten Zuberbier, Ana Margarida Pereira, João A. Fonseca, Jean Bousquet, Bernardo Sousa‐Pinto   +75 more
wiley   +1 more source

Effect of nebulized budesonide on respiratory mechanics and oxygenation in acute lung injury/acute respiratory distress syndrome: Randomized controlled study

Saudi Journal of Anaesthesia, 2017
Background: We tested the hypothesis that nebulized budesonide would improve lung mechanics and oxygenation in patients with early acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS) during protective mechanical ventilation strategy
Hatem Saber Mohamed, Mona Mohamed Abdel Meguid   +1 more
doaj   +1 more source

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J, Boner AL, Bridgman A, Callen J, Delescluse J, Dooms-Goossens AE, Dykes PJ, Falcoz C, Fisher DA, Goossens A, Harding SM, Hogger P, James M, Johnson M, Johnson M, Juhlin L, Katz HI, Korting HC, Lebwohl M, Li JT, Liu XQ, Llewellyn-Jones CG, Lucky AW, McKenzie AW, McLean HM, Nurnberger FG, Phillipps GH, Roberts DT, Spencer CM, Tharp MD, Venning VA, Wilkinson SM, Wolkerstorfer A, Young MMR   +33 more
core   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

COMPARATIVE COST-MINIMIZATION AND BUDGET-IMPACT ANALYSIS OF FIXED-DOSE INHALED CORTICOSTEROID / LONG-ACTING BETAAGONIST COMBINATIONS IN THE TREATMENT OF ASTHMA

Фармакоэкономика, 2017
Comparative pharmacoeconomic analysis of fixed-dose combinations (FDC) vilanterol / fluticasone furoate vs budesonide / formoterol was needed to identify the preferable FDC for asthma management.Study objective: to identify the preferable FDC of inhaled ...
N. L. Pogudina, E. G. Kosolapov, F. S. Kochenkov, A. V. Karaulov, N. L. Bondarenko, D. V. Blinov   +5 more
doaj   +1 more source

New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma [PDF]

, 2017
Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma.
Thomson, Neil C.
core   +1 more source