Results 91 to 100 of about 2,339 (195)

Advancement in research of anti-cancer effects of toad venom (ChanSu) and perspectives

open access: yesWorld Journal of Traditional Chinese Medicine, 2015
Toad venom, called as ChanSu in China, is a widely used traditional Chinese medicine (TCM) whose active components are mainly bufadienolides. ChanSu could exhibit cardiotonic, anti-microbial, anti-inflammatory and, most importantly, anti-cancer effects ...
Miao Liu   +4 more
doaj   +1 more source

Tris(pentafluorophenyl)borane and beyond: modern advances in borylation chemistry [PDF]

open access: yes, 2017
As main-group chemistry, in particular boron chemistry, has expanded and developed over the past 20 years, one reagent has risen to prominence as well.
James R. Lawson   +3 more
core   +2 more sources

Picrasidine I Regulates Apoptosis in Melanoma Cell Lines by Activating ERK and JNK Pathways and Suppressing AKT Signaling

open access: yesEnvironmental Toxicology, Volume 39, Issue 12, Page 5309-5320, December 2024.
ABSTRACT World Health Organization data indicate a continuous increase in melanoma incidence, with metastatic melanoma characterized by poor prognosis and drug resistance. The exploration of therapeutics derived from natural products remains an active area of in vitro research. The aim of this study was to determine the antitumor effects of picrasidine
Mu‐Kuei Shieu   +5 more
wiley   +1 more source

Eucalyptus globulus L. extract as an antifungal agent against Candida species [PDF]

open access: yes, 2014
Hundreds of botanical preparations have been prepared and used for a wide variety of conditions. Different studies have been carried out towards to confirm the effective multitude of health benefits provided by medicinal plants [I].
Barros, Lillian   +4 more
core  

Coevolutionary escalation led to differentially adapted paralogs of an insect's Na,K‐ATPase optimizing resistance to host plant toxins

open access: yesMolecular Ecology, Volume 33, Issue 14, July 2024.
Abstract Cardiac glycosides are chemical defence toxins known to fatally inhibit the Na,K‐ATPase (NKA) throughout the animal kingdom. Several animals, however, have evolved target‐site insensitivity through substitutions in the otherwise highly conserved cardiac glycoside binding pocket of the NKA. The large milkweed bug, Oncopeltus fasciatus, shares a
Marlena Herbertz   +5 more
wiley   +1 more source

Escalation by duplication: Milkweed bug trumps Monarch butterfly

open access: yesMolecular Ecology, Volume 33, Issue 14, July 2024.
The iconic Monarch butterfly is probably the best‐known example of chemical defence against predation, as pictures of vomiting naive blue jays in countless textbooks vividly illustrate. Larvae of the butterfly take up toxic cardiac glycosides from their milkweed hostplants and carry them over to the adult stage.
Franziska Beran, David G. Heckel
wiley   +1 more source

Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses

open access: yesMedicina, 2019
Drimia indica (Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments.
Sonali Aswal   +6 more
doaj   +1 more source

Genotoxic and cytotoxic potential of whole plant extracts of Kalanchoe laciniata by Ames and MTT assay [PDF]

open access: yes
Lack of data on safety of herbal medicines have endangered human health and life. The present study evaluated the genotoxic and mutagenic effect of Kalanchoe laciniata to access the safety and usefulness of the medicinal plant.
Ahmed, Shoaib   +9 more
core   +1 more source

Cinobufotalin prevents bone loss induced by ovariectomy in mice through the BMPs/SMAD and Wnt/β‐catenin signaling pathways

open access: yesAnimal Models and Experimental Medicine, Volume 7, Issue 3, Page 208-221, June 2024.
Cinobufotalin (Hua‐chan‐su, a traditional Chinese medicine) prevents bone loss. Abstract Background Osteoporosis is a chronic bone disease characterized by bone loss and decreased bone strength. However, current anti‐resorptive drugs carry a risk of various complications.
Da‐zhuang Lu   +10 more
wiley   +1 more source

Potential Health Risks Posed by Plant-Derived Cumulative Neurotoxic Bufadienolides in South Africa

open access: yesMolecules, 2016
Bufadienolide-type cardiac glycosides have a worldwide distribution and are mainly synthesized by plants, but there are also animal sources. In South Africa, members of three genera of the Crassulaceae (Cotyledon, Tylecodon and Kalanchoe) cause a unique ...
Christo Botha
doaj   +1 more source

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