Results 71 to 80 of about 1,623 (201)
Biology, 2020 Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%.
Laura Soumoy +8 more
doaj +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.USP13 is a promising therapeutic target for cellular proliferation in multiple myeloma. Bruceine A can retard the development of multiple myeloma by targeting USP13/PARP1‐mediated DNA damage repair and triggering cell apoptosis. ABSTRACT Multiple myeloma (MM) is an incurable hematologic malignancy, driving significant interest in the discovery of novel
Mengjie Guo +9 more
wiley +1 more source
Anti-gastric cancer activity in three-dimensional tumor spheroids of bufadienolides
, 2016 Multicellular spheroids of cancer cells have been increasingly used to screen anti-tumor compounds, owing to their in vivo like microenvironment and structure as well as compatibility to high-throughput/high-content screening.
Wei, Lai +10 more
core +1 more source
Ecology and Evolution, Volume 15, Issue 4, April 2025.Hatchlings of invasive cane toads respond to the risk of cannibalism by accelerating development but experience significant negative carry‐over effects on fitness in the tadpole stage. Our experiments demonstrate that this hatchling response is induced by chemicals located in the skin of older cannibalistic tadpoles. This response is unique to cannibal
Michael R. Crossland +2 more
wiley +1 more source
, 2015 A quantitative assay for determination of the main bufadienolides bersaldegenin-1-acetate (1), bersaldegenin-3-acetate (2), bryophyllin A (3), and bersaldegenin-1,3,5-orthoacetate (4) in Bryophyllum pinnatum leaves and manufactured products was developed
Potterat, Olivier +6 more
core +1 more source
Food Frontiers, Volume 6, Issue 2, Page 891-908, March 2025.1. This study is the first to demonstrate the anti‐ulcerative colitis efficacy of Taraxasterol acetate (TSA) and its superiority over Taraxacum officinale extract. 2. The mechanism of TSA against ulcerative colitis was explained from the perspective of gut microbiota and metabolome. 3.
Li Jin +8 more
wiley +1 more source
Chemical Warfare Through the Ages: A Systematic Review From Antiquity to the Present
Journal of Toxicology, Volume 2025, Issue 1, 2025.Chemical warfare means the use of chemical agents that have direct toxic effects on animals, plants and humans, as weapons. The first documented use of a chemical agent for warfare purposes occurred in ancient times around 10,000 BCE in South Africa when weapons were dipped in chemicals and then used to attack and defend from enemies.
Damian Alexander Honeyman +4 more
wiley +1 more source
Scientifica, Volume 2025, Issue 1, 2025.This study aims to document plant species used to fight several diseases related to mild COVID‐19 symptoms such as cough, colds, fever, dizziness and diarrhoea in Gorontalo Province, eastern Indonesia. Data were collected from 105 local residents using semistructured questionnaires, open interviews and field surveys.
Wiwied Ekasari +5 more
wiley +1 more source
Structural parameters and binding constants of bufadienolides for HSA at 298 K.
, 2015 Structural parameters and binding constants of bufadienolides for HSA at 298 K.
Honglan Wang (107974) +6 more
core +1 more source
, 2016 Bufadienolides are a major class of bioactive compounds derived from amphibian skin secretion. Recent studies demonstrate that bufadienolides have a promising role in targeted cancer chemotherapy.
Ning, Jing +10 more
core +1 more source