Uncovering the Mechanisms of Active Components from Toad Venom against Hepatocellular Carcinoma Using Untargeted Metabolomics [PDF]
Molecules, 2022 Toad venom, a dried product of secretion from Bufo bufo gargarizans Cantor or Bufo melanostictus Schneider, has had the therapeutic effects of hepatocellular carcinoma confirmed.
Changzhen Sun, Ren Wei, Si-Jin Yang
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Combinational Antitumor Strategies Based on the Active Ingredients of Toad Skin and Toad Venom [PDF]
Drug Design, Development and TherapyHuan Tian,1 Feng Zhao,1 Bao-Sen Yue,1 Bing-Tao Zhai2– 5 1Department of Pharmacy, Xi’an Hospital of Traditional Chinese Medicine, Xi’an, People’s Republic of China; 2College of Pharmacy, Shaanxi University of Chinese Medicine, Xi’an, People’s Republic of ...
Bing-Tao Zhai
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Identification of Antitumor Constituents in Toad Venom by Spectrum-Effect Relationship Analysis and Investigation on Its Pharmacologic Mechanism [PDF]
Molecules, 2020 (1) Background: Toad venom (Bufonis Venenum, known as ‘Chansu’ in Chinese), the secretion of the ear-side gland and skin gland of Bufo gargarizans cantor or Duttaphrynus melanostictus Schneider, has been utilized to treat several diseases in China for ...
Longhu Wang
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A New Indole Alkaloid from the Toad Venom of Bufo bufo gargarizans [PDF]
Molecules, 2016 A new indole alkaloid named bufobutarginine (1), along with three known bufotenines, namely, serotonin (2), bufotenidine (3), and bufotenine (4), were isolated from the water extract of toad venom.
Dong Wang, Dongchun Liu, An-Dong Wang
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Ocular inoculation of toad venom: toxic cataract and proteomic profiling [PDF]
Frontiers in MedicinePurposeTo report a singular case of cataract caused by toad venom inoculation and to scrutinize the pathological mechanisms through proteomic sequencing of the lens specimen.MethodsA young Chinese male presented with progressively deteriorating vision in
Ni Shuang, Yixuan Feng
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Advances on Delivery System of Active Ingredients of Dried Toad Skin and Toad Venom [PDF]
International Journal of NanomedicineDan Zhang, Bingtao Zhai, Jing Sun, Jiangxue Cheng, Xiaofei Zhang, Dongyan Guo State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs
Jing Sun, Dan Zhang, Bingtao Zhai
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Identification of Protein Quality Markers in Toad Venom from Bufo gargarizans [PDF]
Molecules, 2023 Toad venom is a traditional Chinese medicine with high medicinal value. The existing quality evaluation standards of toad venom have obvious limitations because of the lack of research on proteins. Thus, it is necessary to screen suitable quality markers
Meiyun Yang +9 more
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Comparative Analysis of Hydrophilic Ingredients in Toad Skin and Toad Venom Using the UHPLC-HR-MS/MS and UPLC-QqQ-MS/MS Methods Together with the Anti-Inflammatory Evaluation of Indolealkylamines [PDF]
Molecules, 2018 Toad skin and toad venom, as two kinds of Chinese medicine, are prepared from Bufo bufo gargarizans Cantor and Bufo melanostictus Schneider. However, they display distinct properties in traditional application, and the hydrophilic ingredients are the ...
Yu Zhang +9 more
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Toad Venom Antiproliferative Activities on Metastatic Melanoma: Bio-Guided Fractionation and Screening of the Compounds of Two Different Venoms [PDF]
Biology, 2020 Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%.
Laura Soumoy +8 more
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Two New Indole Alkaloids from Toad Venom of Bufo bufo gargarizans [PDF]
Molecules, 2020 Two new indole alkaloids, Bufotenidine B (2) and Bufocarboline A (6), along with seven known indole alkaloids (1, 3–5, and 7–9) and three organic acids (10–12), were isolated from the water extract of toad venom.
Yu-Lin Chen +8 more
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