Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toad [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2014 BackgroundRhinella schneideri, previously known as Bufo paracnemis, is a common toad in many regions of Brazil. Its venom exerts important cardiovascular effects on humans and other animals.
Sandro Rostelato-Ferreira +4 more
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Toad venom-derived bufadienolides and their therapeutic application in prostate cancers: Current status and future directions [PDF]
Frontiers in Chemistry, 2023 Cancer is the second leading cause of death worldwide. Specially, the high incidence rate and prevalence of drug resistance have rendered prostate cancer (PCa) a great threat to men’s health.
Qingmei Ye +4 more
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Identification and Comparative Evaluation of Analgesic Components in Toad Venom on Inflammatory Pain [PDF]
Journal of Inflammation ResearchYuting Wen, Ruixiang Li, Xialian Cui, Fang Zhang, Jiange ZhangInnovation Research Institute of Traditional Chinese Medicine (IRI), Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People’s Republic of China*These authors ...
Wen Y, Li R, Cui X, Zhang F, Zhang J
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Toxins, 2021 Animal venoms, widespread throughout the world, are complex mixtures, the composition of which depends on the venom-producing species. The objective of this study was to contribute to the development of animal venom-based medicines by investigating the ...
Soo-Hyun Sung +5 more
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Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins [PDF]
Molecules, 2019 Toad venom (Chansu), a traditional Chinese medicine (TCM), has been widely used for treating various cancer. However, it is considerably difficult to evaluate the quality of Chansu due to its complex chemical compositions.
Yueting Cao +3 more
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Intoxicação por veneno de sapo em um canino Toad venom intoxication in a dog [PDF]
Ciência Rural, 2008 O sapo do gênero Bufo possui nas suas glândulas paratóides uma secreção mucóide contendo toxinas como bufaginas e Bufotoxinas, que são esteróides cardiogênicos. Os cães podem atacar os sapos, entrando em contato com o veneno por meio das mucosas.
Luciana Sonne +6 more
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Clinical and electrocardiographic evaluation during experimental toad poisoning in dogs [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2010 Accidents involving toad poisoning are frequent and dogs are the most common victims; they become poisoned by biting or ingesting a toad. When released in the organism, the venom is absorbed by both the oral mucosa and the digestive tract, initiating its
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Isolation, Identification and Chemical Modification of Bufadienolides from Bufo melanostictus Schneider and Their Cytotoxic Activities against Prostate Cancer Cells [PDF]
MoleculesThe traditional Chinese medicine toad venom (Venenum bufonis) has been extensively used to treat various diseases, including cancers, in China and other Southeast Asian countries.
Qingmei Ye +4 more
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Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway [PDF]
Immunity, Inflammation and DiseaseBackground Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities.
Xixi Liu +11 more
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Chemical and Biological Technologies in AgricultureBackground As a valuable agricultural product derived primarily from cultivated toads, toad venom has been widely used for its significant antitumor properties in pharmacological formulations. However, the structural and biological characteristics of its
Feng Pan +9 more
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