Two New Indole Alkaloids from Toad Venom of Bufo bufo gargarizans [PDF]
Molecules, 2020 Two new indole alkaloids, Bufotenidine B (2) and Bufocarboline A (6), along with seven known indole alkaloids (1, 3–5, and 7–9) and three organic acids (10–12), were isolated from the water extract of toad venom.
Yu-Lin Chen +8 more
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Identification of anti-tumor components from toad venom. [PDF]
Oncol Lett, 2017 Secretion of granular glands from the skin of amphibians is a fascinating resource of active substances, particularly for cancer therapy in clinical practice of Traditional Chinese Medicine. A variety of anti-tumor peptides have been isolated from different toads and frogs; however, no anti-tumor peptides are reported in toad venom of Bufo gargarizans.
Gao F +6 more
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Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins [PDF]
Molecules, 2019 Toad venom (Chansu), a traditional Chinese medicine (TCM), has been widely used for treating various cancer. However, it is considerably difficult to evaluate the quality of Chansu due to its complex chemical compositions.
Yueting Cao +3 more
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An experimental study on the anti-Ehrlich ascites carcinoma effect of purified toad venom extract. [PDF]
Afr J Tradit Complement Altern Med, 2013 The objective of this paper was to study the anti-Ehrlich ascites carcinoma effect of purified toad venom extract and its mechanism. Mouse model of Ehrlich ascites carcinoma was established with cisplatin as the control to observe the inhibitory effect ...
Wang Y.
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Isolation, Identification and Chemical Modification of Bufadienolides from Bufo melanostictus Schneider and Their Cytotoxic Activities against Prostate Cancer Cells [PDF]
MoleculesThe traditional Chinese medicine toad venom (Venenum bufonis) has been extensively used to treat various diseases, including cancers, in China and other Southeast Asian countries.
Qingmei Ye +4 more
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Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway [PDF]
Immunity, Inflammation and DiseaseBackground Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities.
Xixi Liu +11 more
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3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation [PDF]
Natural Products and BioprospectingBufadienolides, naturally occurring steroids primarily found in toads, have garnered attention for their pharmacological properties and ecological significance.
Li-Jun Ruan +2 more
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Cellular and molecular mechanisms of arenobufagin in cancer therapy: a systematic review [PDF]
Discover OncologyThe search for effective and safe therapeutic options is the goal of clinical treatment for cancer patients. In recent years, natural products have received increasing attention in order to develop new drugs with good antitumor effects and fewer side ...
Si-Jun Wang +5 more
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Toxins, 2021 Animal venoms, widespread throughout the world, are complex mixtures, the composition of which depends on the venom-producing species. The objective of this study was to contribute to the development of animal venom-based medicines by investigating the ...
Soo-Hyun Sung +5 more
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Toxins, 2021 Snakes of the genera Pseudocerastes and Eristicophis (Viperidae: Viperinae) are known as the desert vipers due to their association with the arid environments of the Middle East.
Bianca op den Brouw +14 more
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