Results 41 to 50 of about 45,960 (145)
Pesquisa Veterinária Brasileira, 2009 Dentre os sinais sistêmicos causados pelo envenenamento por veneno de sapo (bufotoxina) em cães, os efeitos cardiotóxicos são um dos mais importantes. O objetivo deste estudo foi avaliar as potenciais alterações no músculo cardíaco de cães envenenados ...
Annelise C. Camplesi +3 more
doaj +1 more source
Bufalin suppresses ovarian cancer cell proliferation via EGFR pathway
Chinese Medical Journal, 2022 . Background:. Previous studies have shown that bufalin exerts antitumor effects through various mechanisms. This study aimed to determine the antineoplastic mechanism of bufalin, an extract of traditional Chinese medicine toad venom, in ovarian cancer ...
Lei Dou +7 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells. [PDF]
PLoS ONE, 2016 Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough.
Qingxi Yue +9 more
doaj +1 more source
Molecules, 2021 Toads in the family Bufonidae contain bufadienolides in their venom, which are characterized by their chemical diversity and high pharmacological potential.
Candelario Rodriguez +6 more
doaj +1 more source
European Journal of Social Psychology, EarlyView.ABSTRACT Many important historical and contemporary ethical debates (e.g., on slavery, abortion and environmental protection) reflect disagreements about what we owe to different groups of individuals. Recent work in moral psychology has uncovered a seemingly replicable hierarchy of moral concern, but these studies were conducted in a few countries ...
Işıl Ayça Akkuş +4 more
wiley +1 more source
Resibufogenin and cinobufagin activate central neurons through an ouabain-like action. [PDF]
PLoS ONE, 2014 Cinobufagin and resibufogenin are two major effective bufadienolides of Chan su (toad venom), which is a Chinese medicine obtained from the skin venom gland of toads and is used as a cardiotonic and central nervous system (CNS) respiratory agent, an ...
Ze-Jun Wang +2 more
doaj +1 more source
Journal of Animal Ecology, EarlyView.Conspicuous colouration signals venomous nature throughout snakes. Abstract Many animals use conspicuous colours to advertise their unprofitability to potential predators, a phenomenon known as aposematism. For example, conspicuous banded patterns in snakes are often highlighted as aposematic signalling of their venomous nature.
Amy Duclaux, Michel Dugon, Kevin Healy
wiley +1 more source
Integrative Zoology, EarlyView.Brain size may be influenced by the cognitive demands of sociality (social brain hypothesis). We used microCT to compare CNS and brain volumes in social versus solitary huntsman and crab spiders. Social huntsman spiders had larger arcuate and mushroom bodies, while social crab spiders had larger visual neuropils.
Vanessa Penna‐Gonçalves +6 more
wiley +1 more source
The Paraguayan Rhinella toad venom: Implications in the traditional medicine and proliferation of breast cancer cells [PDF]
, 2017 © 2017 Elsevier Ireland Ltd Ethnopharmacological relevance Toads belonging to genus Rhinella are used in Paraguayan traditional medicine to treat cancer and skin infections.
Urra, Félix A. +9 more
core +1 more source