Results 61 to 70 of about 45,960 (145)
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation
Pharmacology Research & Perspectives, 2021 Toads have high medicinal value and have been used for medicinal purposes since the Tang Dynasty period (7th‐10th Century AD). Bufarenogin, an active anti‐tumor constituent of toad venom, shows anti‐tumor activity.
Qinrui Han +5 more
doaj +1 more source
Pharmaceutical Biology, 2022 Context Acute promyelocytic leukaemia (APL) is a malignant hematological tumour characterized by the presence of promyelocytic leukaemia–retinoic acid receptor A (PML-RARA) fusion protein. Cinobufagin (CBG) is one of the main effective components of toad
Yaoyao Bian +10 more
doaj +1 more source
Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha +4 more
wiley +1 more source
Toad venom intoxication in a dog [PDF]
, 2008 O sapo do gênero Bufo possui nas suas glândulas paratóides uma secreção mucóide contendo toxinas como bufaginas e bufotoxinas, que são esteróides cardiogênicos. Os cães podem atacar os sapos, entrando em contato com o veneno por meio das mucosas.
Rozza, Daniela +6 more
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Relational knowing as method and practice
People and Nature, Volume 8, Issue 10, Page 3585-3600, October 2026.Abstract This paper seeks to contribute to (re)building the capacity for embodied, place‐based relational knowing, transforming how we know and thus what we know. What is known, or sought to be known, is relations. How we know these relations is by already being in it: breathing, sensing, moving, listening, responding, affecting and being affected ...
Katie Moon
wiley +1 more source
Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]
, 2011 Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Jacoby-Alner, T.E. +5 more
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Biological characterization of Bothrops marajoensis snake venom
, 2011 This study describes the effects of Bothrops marajoensis venom (Marajó lancehead) on isolated neuromuscular preparations of chick biventer cervicis (CBC) and mouse phrenic nerve-diaphragm (PND).
Marangoni, Sérgio +10 more
core +3 more sources
Functional Ecology, Volume 40, Issue 10, Page 3048-3062, October 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Snake venoms show variability in composition at all taxonomic levels, both within and between species, and the selective pressures underlying this variation have long been debated.
Bálint Üveges +17 more
wiley +1 more source
, 2022 Trypanosomiasis afflicts about 6 ~ 7 million people globally and to a large extent impedes livestock production in Africa. Naturally, trypanosomal parasites undergo genetic mutation and have developed resistance over a wide range of therapies.
S., Attah A. +20 more
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Antiproliferative activity and chemical composition of the venom from the Amazonian toad Rhinella marina (Anura: Bufonidae) [PDF]
, 2016 Little is known on the composition of Peruvian Amazon toad venoms. The large toad Rhinella marina is common in the cleared tropical forests of the Iquitos region and is regarded as poisonous. The venom from two different populations of R.
Cárdenas Matus, Julio +5 more
core +1 more source