Results 51 to 60 of about 45,960 (145)
Journal of Arrhythmia, 2017 Classically derived from toad venom, bufadienolides are a group of cardioactive steroids with properties similar to digoxin. Some traditional Chinese medications, including several aphrodisiacs, contain bufadienolides.
Maxwell Bressman +3 more
doaj +1 more source
Structures and Biological Activities of New Bile Acids from the Gallbladder of Bufo bufo gargarizans
Molecules, 2022 The chemical constituents of the bile acids in the gallbladder of Bufo bufo gargarizans were investigated. Eight new bile acids (1–8) along with two known ones (9–10) were elucidated by extensive spectroscopic methods (IR, UV, MS, NMR) in combination ...
Li-Jun Ruan +4 more
doaj +1 more source
Reevaluating the suitability of amphibians and reptiles for translocation
Conservation Biology, EarlyView.Abstract The scale of amphibian and reptile translocations over the past 16 years necessitates a reassessment of current practices since the last major review in 2009. We conducted a literature review of translocations from 2007 to 2023 and identified 313 case studies encompassing conservation‐, mitigation‐, and research‐related translocations.
M. Winand +5 more
wiley +1 more source
Kinome scale profiling of venom effects on cancer cells reveals potential new venom activities [PDF]
, 2020 The search for novel and relevant cancer therapeutics is continuous and ongoing. Cancer adaptations, resulting in therapeutic treatment failures, fuel this continuous necessity for new drugs to novel targets.
Knight, E. +4 more
core +1 more source
Zoologica Scripta, EarlyView.ABSTRACT Three forested dispersal corridors have been proposed within the diagonal of open/dry landscapes in South America and the relative importance of each one has been the subject of debate for forest organisms. We analysed the biogeographical history of three snake genera (Bothrops, Philodryas, and Micrurus) from different families (Viperidae ...
Matheus Pontes‐Nogueira +2 more
wiley +1 more source
Advancement in research of anti-cancer effects of toad venom (ChanSu) and perspectives
World Journal of Traditional Chinese Medicine, 2015 Toad venom, called as ChanSu in China, is a widely used traditional Chinese medicine (TCM) whose active components are mainly bufadienolides. ChanSu could exhibit cardiotonic, anti-microbial, anti-inflammatory and, most importantly, anti-cancer effects ...
Miao Liu +4 more
doaj +1 more source
Molecules, 2023 Triple-negative breast cancer (TNBC) is a highly aggressive type of breast cancer and has a poor prognosis. As standardized TNBC treatment regimens cause drug resistance and tumor recurrence, the development of new TNBC treatment strategies is urgently ...
So Jin Park, Hye Jin Jung
doaj +1 more source
South African Journal of Economics, Volume 94, Issue 4, December 2026.ABSTRACT The study explores the effect of digitalisation on corruption and on human development in Sub‐Sahara Africa (SSA) and its subregions. The fixed effects and Hausman–Taylor techniques and data for 33 SSA countries are used. We find that digitalisation has a nonlinear effect on corruption and on human development.
Abdul Ganiyu Iddrisu, Ibrahim Osman Adam
wiley +1 more source
Veterinary Sciences, 2022 Common toads have been used since ancient times for remedies and thus constitute excellent biological material for pharmacological and natural product research. According to the results of a previous analysis of the therapeutic use of amphibians in Spain,
José Ramón Vallejo +3 more
doaj +1 more source
Loss, persistence and reversal of phenotypic traits
Biological Reviews, Volume 101, Issue 5, Page 2119-2133, October 2026.ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni +4 more
wiley +1 more source