Molecules, 2021 Toads in the family Bufonidae contain bufadienolides in their venom, which are characterized by their chemical diversity and high pharmacological potential.
Candelario Rodriguez +6 more
doaj +1 more source
Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators [PDF]
, 2017 Animals using toxic peptides and proteins for predation or defense typically depend on specialized morphological structures, like fangs, spines, or a stinger, for effective intoxication.
Ballet, Steven +12 more
core +1 more source
Resibufogenin and cinobufagin activate central neurons through an ouabain-like action. [PDF]
PLoS ONE, 2014 Cinobufagin and resibufogenin are two major effective bufadienolides of Chan su (toad venom), which is a Chinese medicine obtained from the skin venom gland of toads and is used as a cardiotonic and central nervous system (CNS) respiratory agent, an ...
Ze-Jun Wang +2 more
doaj +1 more source
Are ticks venomous animals? [PDF]
, 2017 [Introduction]: As an ecological adaptation venoms have evolved independently in several species of Metazoa. As haematophagous arthropods ticks are mainly considered as ectoparasites due to directly feeding on the skin of animal hosts. Ticks are of major
Cabezas-Cruz, Alejandro +1 more
core +1 more source
Anti-trypanosomal Activity of Bufonidae (Toad) Venom Crude Extract on Trypanosoma brucei brucei in Swiss Mice [PDF]
, 2022 Trypanosomiasis afflicts about 6 ~ 7 million people globally and to a large extent impedes livestock production in Africa. Naturally, trypanosomal parasites undergo genetic mutation and have developed resistance over a wide range of therapies.
A., Adejoh V. +20 more
core +2 more sources
Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin
Angewandte Chemie International Edition, EarlyView.We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu +3 more
wiley +1 more source
“Paltrie vermin, cats, mise, toads, and weasils”: witches, familiars, and human-animal interactions in the English witch trials [PDF]
, 2019 This article explores the role played by the relationship between witch and familiar in the early modern witch trials. It positions animal familiars at the intersection of early modern belief in witchcraft and magic, examining demonologies, legal and ...
Parish, Helen
core +1 more source
A neuro‐behavioural model of neophobia
Biological Reviews, EarlyView.ABSTRACT Fear can be defined as the internal neurological state that releases a repertoire of behaviours an animal performs to reduce the effect of an aversive factor. Neophobia, the fear of novelty, is a fundamental behavioural trait observed across a wide range of species from arthropods to humans.
Arik Dorfman, Aziz Subach, Inon Scharf
wiley +1 more source
Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in the State of the Art [PDF]
, 2015 published_or_final_versio
Feng, Y, Wang, N
core +3 more sources
Ecology and evolution of pyrazines in insects
Biological Reviews, EarlyView.ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk +2 more
wiley +1 more source