Results 21 to 30 of about 45,960 (145)

Cellular and molecular mechanisms of arenobufagin in cancer therapy: a systematic review [PDF]

Discover Oncology
The search for effective and safe therapeutic options is the goal of clinical treatment for cancer patients. In recent years, natural products have received increasing attention in order to develop new drugs with good antitumor effects and fewer side ...
Si-Jun Wang, Peng-Xin Wang, Hai-Ling Ding, Yuan-Yuan Qi, Ya-Ru Song, Xiao-Nan Mu   +5 more
doaj   +2 more sources

An experimental study on the anti-Ehrlich ascites carcinoma effect of purified toad venom extract. [PDF]

Afr J Tradit Complement Altern Med, 2013
The objective of this paper was to study the anti-Ehrlich ascites carcinoma effect of purified toad venom extract and its mechanism. Mouse model of Ehrlich ascites carcinoma was established with cisplatin as the control to observe the inhibitory effect ...
Wang Y.
europepmc   +2 more sources

Extensive Variation in the Activities of Pseudocerastes and Eristicophis Viper Venoms Suggests Divergent Envenoming Strategies Are Used for Prey Capture

Toxins, 2021
Snakes of the genera Pseudocerastes and Eristicophis (Viperidae: Viperinae) are known as the desert vipers due to their association with the arid environments of the Middle East.
Bianca op den Brouw, Francisco C. P. Coimbra, Lachlan A. Bourke, Tam Minh Huynh, Danielle H. W. Vlecken, Parviz Ghezellou, Jeroen C. Visser, James S. Dobson, Manuel A. Fernandez-Rojo, Maria P. Ikonomopoulou, Nicholas R. Casewell, Syed A. Ali, Behzad Fathinia, Wayne C. Hodgson, Bryan G. Fry   +14 more
doaj   +1 more source

Studies on toad venom (3): effect of metals on the quality of toad venom torrefied on a metal plate. [PDF]

, 2002
To study the quality of toad venom dried on different metal plates by heating at 105 degrees C, each 20 g sample of fresh toad venom collected in Hei-Long-Jiang Province, China, was dried on (1) brass, (2) copper, (3) glass, (4) acrylic resins, (5 ...
112, 50115193, 26572, Kawahara, Kazuhito, Mikage, Masayuki   +4 more
core   +2 more sources

Ocular Hypotonia and Transient Decrease of Vision as a Consequence of Exposure to a Common Toad Poison

Case Reports in Ophthalmological Medicine, 2020
The common toad produces venom (bufotoxin) that is produced in the parotid gland of the toad as well as in the skin. This toxic compound is a potent inhibitor of Na+/K+-ATPase activity. Physiological effects of bufotoxin are similar to those of digitalis
Renato Pejic, Marija Simic Prskalo, Josip Simic   +2 more
doaj   +1 more source

Clinical effectiveness of hymenoptera venom immunotherapy [PDF]

, 2013
Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Scheipl, Fabian, Darsow, Ulf, Reider, Norbert, Bonifazi, Floriano, Aberer, Werner, Schmid-Grendelmeier, Peter, Ruëff, Franziska, Treudler, Regina, Biló, Maria Beatrice, Sturm, Gunter Johannes, Küchenhoff, Helmut, Severino, Maurizio, Wüthrich, Brunello, Seitz, Michael J., Quercia, Oliviero, Bodzenta-Lukaszyk, Anna, Lang, Roland, Haeberli, Gabrielle, Campi, Paolo, Hawranek, Thomas, Müller, Ulrich, Przybilla, Bernhard   +21 more
core   +1 more source

An overview of the past decade of bufalin in the treatment of refractory and drug-resistant cancers: current status, challenges, and future perspectives

Frontiers in Pharmacology, 2023
Profound progress has been made in cancer treatment in the past three decades. However, drug resistance remains prevalent and a critical challenge.
Qingmei Ye, Qingmei Ye, Xin Zhou, Han Ren, Fangxuan Han, Rong Lin, Juan Li   +6 more
doaj   +1 more source

Pharmacological aspects of Vipera xantina palestinae venom [PDF]

, 2011
In Israel, Vipera xantina palestinae (V.x.p.) is the most common venomous snake, accounting for several hundred cases of envenomation in humans and domestic animals every year, with a mortality rate of 0.5 to 2%.
Katzhendler, Jeoshua, Franziska T. Arlinghaus, Jeoshua Katzhendler, Cezary Marcinkiewicz, Philip Lazarovici, Arlinghaus, Franziska T., Johannes A. Eble, Lazarovici, Philip, Momic, Tatjana, Eble, Johannes A., Hadar Arien-Zakay, Marcinkiewicz, Cezary, Tatjana Momic, Arien-Zakay, Hadar, Arlinghaus, Franziska Therese   +14 more
core   +1 more source

Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads

Molecules, 2022
Cardiotonic steroids (CTS) were first documented by ancient Egyptians more than 3000 years ago. Cardiotonic steroids are a group of steroid hormones that circulate in the blood of amphibians and toads and can also be extracted from natural products such ...
Hesham R. El-Seedi, Nermeen Yosri, Bishoy El-Aarag, Shaymaa H. Mahmoud, Ahmed Zayed, Ming Du, Aamer Saeed, Syed G. Musharraf, Islam M. El-Garawani, Mohamed R. Habib, Haroon Elrasheid Tahir, Momtaz M. Hegab, Xiaobo Zou, Zhiming Guo, Thomas Efferth, Shaden A. M. Khalifa   +15 more
doaj   +1 more source

Novel Strategies for Solubility and Bioavailability Enhancement of Bufadienolides

Molecules, 2021
Toad venom contains a large number of bufadienolides, which have a variety of pharmacological activities, including antitumor, cardiovascular, anti-inflammatory, analgesic and immunomodulatory effects.
Huili Shao, Bingqian Li, Huan Li, Lei Gao, Chao Zhang, Huagang Sheng, Liqiao Zhu   +6 more
doaj   +1 more source