Results 51 to 60 of about 1,623 (201)
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Advanced Science, Volume 13, Issue 23, 23 April 2026.Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source
Molecular docking of various bufadienolides to HSA.
, 2015 HSA = human serum albumin; MD score = MolDock score.Molecular docking of various bufadienolides to HSA.
Honglan Wang (107974) +6 more
core +1 more source
VIEW, Volume 7, Issue 2, April 2026.This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu +7 more
wiley +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, Volume 111, Issue 3, Page 653-673, 1 March 2026.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Effect of bufadienolides on H22 and MFC tumors.
, 2017 Effect of bufadienolides on H22 and MFC tumors.
Xiaolu Wei (3204066) +8 more
core +1 more source
Journal of Pharmacopuncture, 2012 Objectives: Toad venom, called Chan-Su, is a traditional Oriental medicine secreted from the auricular and the skin glands of the Bufo bufo gargarizanz Cantor or B.
Lee Hyo-Jae +6 more
doaj +1 more source
Evaluation of Bufadienolides as the Main Antitumor Components in Cinobufacin Injection for Liver and Gastric Cancer Therapy. [PDF]
PLoS ONE, 2017 Cinobufacin injection, also known as huachansu, is a preparation form of Cinobufacini made from Cinobufacin extract liquid. Despite that Cinobufacin injection is shown to shrink liver and gastric tumors, improving patient survival and life quality, the ...
Xiaolu Wei +8 more
doaj +1 more source
Amphibian Strategies Against Attacks by Flies: Host‐Specificity and Threats
Ecology and Evolution, Volume 16, Issue 1, January 2026.Species interactions between Diptera flies and amphibians play a significant role in tropical ecosystems, but their ecology and evolution remain understudied. This review explores the costs flies impose on amphibians, such as pathogen transmission and disruption of communication systems, and highlights the evolutionary strategies employed by both ...
Leonardo Leite Ferraz de Campos +3 more
wiley +1 more source
Effect of bufadienolides on HepG-2 and MKN-45 tumors.
, 2017 Effect of bufadienolides on HepG-2 and MKN-45 tumors.
Xiaolu Wei (3204066) +8 more
core +1 more source
Advancement in research of anti-cancer effects of toad venom (ChanSu) and perspectives
World Journal of Traditional Chinese Medicine, 2015 Toad venom, called as ChanSu in China, is a widely used traditional Chinese medicine (TCM) whose active components are mainly bufadienolides. ChanSu could exhibit cardiotonic, anti-microbial, anti-inflammatory and, most importantly, anti-cancer effects ...
Miao Liu +4 more
doaj +1 more source