Results 41 to 50 of about 2,364 (200)

High Resolution Mass Profile of Bufadienolides and Peptides Combing with Anti-Tumor Cell Screening and Multivariate Analysis for the Quality Evaluation of Bufonis Venenum

open access: yesMolecules, 2019
In order to evaluate the quality of Bufonis Venenum commercial herbs, a three-step qualitative and quantitative research study was performed. Firstly, we tried to identify small molecules and peptides in Bufonis Venenum using pre-fractionation ...
Rongrong He   +11 more
doaj   +1 more source

Rhinovirus inhibition by bufadienolides.

open access: yesChemical and Pharmaceutical Bulletin, 1988
An evaluation of thirty-four bufadienolides and two related cardenolides against a series of rhinoviruses in vitro has been completed. Most of the bufadienolides were found to display some inhibitory activity. Scillarenin and 3-O-[N-(tert-butoxycarbonyl)hydrazido]succinylbufalin were found to be the most active with chemotherapeutic indices of 32 and ...
Y, Kamano   +4 more
openaire   +3 more sources

In-silico analysis of bufadienolides as potential inhibitors of Trypanosoma nucleoside hydrolase

open access: yesChemical Physics Impact, 2023
Trypanosomiasis is one of the neglected tropical diseases which curtails the productivity of the victim and causes mortality in extreme cases. Non-availability of vaccines, low therapeutic index of trypanocidal drugs and development of resistance lead to
Shalaka R. Sawant   +6 more
doaj   +1 more source

Predation on invasive cane toads (Rhinella marina) by native Australian rodents [PDF]

open access: yes, 2015
© 2014, Springer-Verlag Berlin Heidelberg. The success of an invasive species can be reduced by biotic resistance from the native fauna. For example, an invader that is eaten by native predators is less likely to thrive than one that is invulnerable. The
Cabrera-Guzmán, E   +4 more
core   +1 more source

Chemical defense of toad tadpoles under risk by four predator species

open access: yesEcology and Evolution, 2019
Many organisms use inducible defenses as protection against predators. In animals, inducible defenses may manifest as changes in behavior, morphology, physiology, or life history, and prey species can adjust their defensive responses based on the ...
Bálint Üveges   +7 more
doaj   +1 more source

Does The Glucocorticoid Stress Response Make Toads More Toxic? An Experimental Study on The Regulation of Bufadienolide Toxin Synthesis [PDF]

open access: yes, 2023
Chemical defense is a crucial component of fitness in many organisms, yet the physiological regulation of defensive toxin synthesis is poorly understood, especially in vertebrates.
Bókony, Veronika   +7 more
core   +2 more sources

Using genetic data to predict the vulnerability of a native predator to a toxic invader [PDF]

open access: yes, 2016
Australia has no native toad species, and as a consequence, many Australian predators lack resistance to the toxins of the invasive cane toad Rhinella marina, and die if they ingest one of these toads.
Armstrong, K.   +5 more
core   +2 more sources

Assessment of neuropharmacological potential of low molecular weight components extracted from Rhinella schneideri toad poison

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2019
Background: Studies on toad poison are relevant since they are considered a good source of toxins that act on different biological systems. Among the molecules found in the toad poison, it can be highlighted the cardiotonic heterosides, which have a ...
Mateus Amaral Baldo   +8 more
doaj   +1 more source

Antimicrobial Secretions of Toads (Anura, Bufonidae): Bioactive Extracts and Isolated Compounds against Human Pathogens

open access: yesAntibiotics, 2020
Species of the family Bufonidae, better known as true toads, are widespread and produce bioactive substances in the secretions obtained from specialized skin macroglands.
Candelario Rodriguez   +4 more
doaj   +1 more source

Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivo [PDF]

open access: yes, 2015
Background: Chansu is a transitional Chinese medicine that has been used for centuries as therapy for inflammation, anaesthesia and arrhythmia in China and other Asian countries. Recently, it has also been used for anti-cancer purposes.
Cao, Siyu   +6 more
core   +1 more source

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