Results 31 to 40 of about 2,364 (200)

From Ethnomedicine to Plant Biotechnology and Machine Learning: The Valorization of the Medicinal Plant Bryophyllum sp.

Pharmaceuticals, 2020
The subgenus Bryophyllum includes about 25 plant species native to Madagascar, and is widely used in traditional medicine worldwide. Different formulations from Bryophyllum have been employed for the treatment of several ailments, including infections ...
Pascual García-Pérez, Eva Lozano-Milo, Mariana Landin, Pedro P. Gallego   +3 more
doaj   +1 more source

Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi

Molecules, 2021
Toads in the family Bufonidae contain bufadienolides in their venom, which are characterized by their chemical diversity and high pharmacological potential.
Candelario Rodriguez, Roberto Ibáñez, Luis Mojica, Michelle Ng, Carmenza Spadafora, Armando A. Durant-Archibold, Marcelino Gutiérrez   +6 more
doaj   +1 more source

An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats

Journal of Pharmaceutical Analysis, 2022
Comprehensive characterization of metabolites and metabolic profiles in plasma has considerable significance in determining the efficacy and safety of traditional Chinese medicine (TCM) in vivo.
Wen-Long Wei, Hao-Jv Li, Wen-Zhi Yang, Hua Qu, Zhen-Wei Li, Chang-Liang Yao, Jin-Jun Hou, Wan-Ying Wu, De-An Guo   +8 more
doaj   +1 more source

Spatial variation of epoxyscillirosidine concentrations in Moraea pallida (yellow tulp) in South Africa [PDF]

, 2013
Moraea pallida (yellow tulp) poisoning is economically the most important intoxication of livestock in South Africa. Poisoning varies according to locality, climatic conditions and growth stage of the plant.
Botha, Christo J., Coetser, Heleen, Labuschagne, Leonie, Schultz, Rowena A., Van Der Merwe, Deon   +4 more
core   +3 more sources

Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads

Molecules, 2022
Cardiotonic steroids (CTS) were first documented by ancient Egyptians more than 3000 years ago. Cardiotonic steroids are a group of steroid hormones that circulate in the blood of amphibians and toads and can also be extracted from natural products such ...
Hesham R. El-Seedi, Nermeen Yosri, Bishoy El-Aarag, Shaymaa H. Mahmoud, Ahmed Zayed, Ming Du, Aamer Saeed, Syed G. Musharraf, Islam M. El-Garawani, Mohamed R. Habib, Haroon Elrasheid Tahir, Momtaz M. Hegab, Xiaobo Zou, Zhiming Guo, Thomas Efferth, Shaden A. M. Khalifa   +15 more
doaj   +1 more source

Bersaldegenin-1,3,5-orthoacetate induces caspase-independent cell death, DNA damage and cell cycle arrest in human cervical cancer HeLa cells

Pharmaceutical Biology, 2021
Context Bufadienolide compounds occur in many plants and animal species and have strong cardiac and anti-inflammatory properties. The compounds have been recently investigated for cytotoxic and antitumor activity.
Justyna Stefanowicz-Hajduk, Magdalena Gucwa, Barbara Moniuszko-Szajwaj, Anna Stochmal, Anna Kawiak, J. Renata Ochocka   +5 more
doaj   +1 more source

Bufothionine induced the mitochondria-mediated apoptosis in H22 liver tumor and acute liver injury [PDF]

, 2015
BACKGROUND: Bufothionine is an alkaloid in Cinobufacini (Huachansu). This study aims to investigate the effects of bufothionine on liver tumors and acute liver injury.
Pei-Pei Chen, Rui-Fang Xie, Xin Zhou, Zhi-Cheng Li   +3 more
core   +1 more source

Biological activities of leaf extracts from selected Kalanchoe species and their relationship with bufadienolides content

Pharmaceutical Biology, 2020
Context Kalanchoe species (Crassulaceae) are widely used in traditional medicine as remedies in infectious diseases and cancer treatment. Objective Cytotoxic and antimicrobial activities of Kalanchoe daigremontiana Raym.-Hamet & H. Perrier, K.
Justyna Stefanowicz-Hajduk, Anna Hering, Magdalena Gucwa, Rafał Hałasa, Agata Soluch, Mariusz Kowalczyk, Anna Stochmal, Renata Ochocka   +7 more
doaj   +1 more source

Phytochemical investigations of three Rhodocodon (Hyacinthaceae Sensu APG II) species [PDF]

, 2017
The genus Rhodocodon (Hyacinthaceae sensu APG II) is endemic to Madagascar and its phytochemistry has not been described previously. The phytochemistry of three species in this genus has been investigated and eight compounds, including three ...
Alaa Alqahtani, Andrius Jaksevicius, Dagne E., Dulcie A. Mulholland, Elizabeth I. Opara, Jackie L. Andriantiana, Moses K. Langat, Pfosser M., Sianne Schwikkard, Tachibana M., Walter Knirsch, Wolfgang Wetschnig   +11 more
core   +2 more sources

Ekstrak Daun Cocor Bebek (Bryophyllum Pinnatum) Sebagai Pengawet Alami Pada Sediaan Sirup Herbal Tomat (Solanum Lycopersicum) [PDF]

, 2013
Synthetic preservatives application in foods continuously, such as formalin can cause a variety of diseases. Alternatives of antimicrobials and preservatives which have less negative impact on health becomes necessary.
Dhiani, B. A. (Binar), Sandi, E. Y. (Elis), Wahyuningrum, R. (Retno)   +2 more
core   +2 more sources