Results 81 to 90 of about 2,364 (200)

Drimia indica: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses

open access: yesMedicina, 2019
Drimia indica (Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments.
Sonali Aswal   +6 more
doaj   +1 more source

Potential Health Risks Posed by Plant-Derived Cumulative Neurotoxic Bufadienolides in South Africa

open access: yesMolecules, 2016
Bufadienolide-type cardiac glycosides have a worldwide distribution and are mainly synthesized by plants, but there are also animal sources. In South Africa, members of three genera of the Crassulaceae (Cotyledon, Tylecodon and Kalanchoe) cause a unique ...
Christo Botha
doaj   +1 more source

Age- and environment-dependent changes in chemical defences of larval and post-metamorphic toads

open access: yesBMC Evolutionary Biology, 2017
Background Chemical defences are widespread in animals, but how their production is adjusted to ecological conditions is poorly known. Optimal defence theory predicts that inducible defences are favoured over constitutive defences when toxin production ...
Bálint Üveges   +5 more
doaj   +1 more source

Ocular Hypotonia and Transient Decrease of Vision as a Consequence of Exposure to a Common Toad Poison

open access: yesCase Reports in Ophthalmological Medicine, 2020
The common toad produces venom (bufotoxin) that is produced in the parotid gland of the toad as well as in the skin. This toxic compound is a potent inhibitor of Na+/K+-ATPase activity. Physiological effects of bufotoxin are similar to those of digitalis
Renato Pejic   +2 more
doaj   +1 more source

Simultaneous Quantification of Seven Major Bufadienolides in Three Traditional Chinese Medicinal Preparations of ChanSu by HPLC-DAD

open access: yesNatural Product Communications, 2009
A high-performance liquid chromatographic method was applied to the determination of gamabufotalin, telocinobufagin, bufotalin, cinobufotalin, bufalin, cinobufagin and resibufogenin in three traditional Chinese medicinal preparations containing ChanSu ...
Xiao Chi Ma   +8 more
doaj   +1 more source

A Comparison of Adrenal in Toad-Eating and Nontoad-Eating Snakes [PDF]

open access: yes, 2011
Toads are chemically defended by bufadienolides, a class of cardiotonic steroids lethal to most predators, including many snakes. Bufadienolides bind to Na+K +-ATPase, inhibiting their ability to transport ions.
Mohammadi, Shabnam
core   +2 more sources

Scanning Electron Microscopic Studies on Leaf Surface in Populations of Urginea Indica Kunth Liliaceae [PDF]

open access: yes, 2013
Scanning electronic microscopic observations on leaf surface in ten populations of Urginea indica of the tribe scilleae are presented. Leaf cuticular ornamentation, stomatal variations and differences, in wax deposition and stomatal frequency play an ...
Geetha, H.L.   +2 more
core  

The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells [PDF]

open access: yes, 2013
Cardiac glycosides are promising anticancer drugs. We have recently shown that the cardiac glycosides digitoxin, digoxin and ouabain induce selective killing of lung cancer cells, and that the cytotoxicity of digitoxin against these cells occurs at ...
Burgos Morón, Estefanía   +2 more
core  

Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases
Background: The resistance against antimalarial drugs represents a global challenge in the fight and control of malaria. The Brazilian biodiversity can be an important tool for research and development of new medicinal products.
Felipe Finger Banfi   +13 more
doaj   +2 more sources

Identification of Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides

open access: yesScientific Reports, 2017
The current study explored the Na+/K+-ATPase (NKA) inhibition-independent proarrhythmic mechanisms of cardiac glycosides (CGs) which are well-known NKA inhibitors. With the cytosolic Ca2+ chelated by EGTA and BAPTA or extracellular Ca2+ replaced by Ba2+,
Cai Hong Koh   +11 more
doaj   +1 more source

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