Age- and environment-dependent changes in chemical defences of larval and post-metamorphic toads
BMC Evolutionary Biology, 2017 Background Chemical defences are widespread in animals, but how their production is adjusted to ecological conditions is poorly known. Optimal defence theory predicts that inducible defences are favoured over constitutive defences when toxin production ...
Bálint Üveges +5 more
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Case Reports in Ophthalmological Medicine, 2020 The common toad produces venom (bufotoxin) that is produced in the parotid gland of the toad as well as in the skin. This toxic compound is a potent inhibitor of Na+/K+-ATPase activity. Physiological effects of bufotoxin are similar to those of digitalis
Renato Pejic +2 more
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Widespread vulnerability of Malagasy predators to the toxins of an introduced toad [PDF]
, 2018 Invasive species are a key factor contributing to the global decline of biodiversity, and understanding the underlying mechanisms is crucial to mitigate detrimental effects [1].
Andreone, Franco +8 more
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Scanning Electron Microscopic Studies on Leaf Surface in Populations of Urginea Indica Kunth Liliaceae [PDF]
, 2013 Scanning electronic microscopic observations on leaf surface in ten populations of Urginea indica of the tribe scilleae are presented. Leaf cuticular ornamentation, stomatal variations and differences, in wax deposition and stomatal frequency play an ...
Geetha, H.L. +2 more
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In vitro cell culture of Charybdis congesta for enhanced production of secondary metabolites: Proscillaridin A, Scillaren A and Scilliroside [PDF]
, 2016 Callus cultures of Charybdis congesta were initiated in vitro and the effect of growth regulators was tested on callus growth and secondary metabolite production.
Devi, P Sita +2 more
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‘Jamaican Stone’: A potentially lethal remedy for delaying ejaculation
Revista Portuguesa de Cardiologia, 2017 Poisoning by ingestion of ‘Jamaican Stone’, a kind of cardioactive steroid, is extremely rare. However, mortality is very high. For this reason, when it occurs, an early and accurate diagnosis represents a critical challenge for clinicians. We present an
Belén Díaz-Antón +7 more
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The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells [PDF]
, 2013 Cardiac glycosides are promising anticancer drugs. We have recently shown that the cardiac glycosides digitoxin, digoxin and ouabain induce selective killing of lung cancer cells, and that the cytotoxicity of digitoxin against these cells occurs at ...
Burgos Morón, Estefanía +2 more
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Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs [PDF]
Journal of Venomous Animals and Toxins including Tropical DiseasesBackground: The resistance against antimalarial drugs represents a global challenge in the fight and control of malaria. The Brazilian biodiversity can be an important tool for research and development of new medicinal products.
Felipe Finger Banfi +13 more
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Cardiac Glycosides in Medicinal Plants [PDF]
, 2017 Plant active metabolites are under intensive examinations around the world to supplement the drugs with minimal side effects. Thus, there is vast potential to explore the possible medicine from the plant sources.
Morsy, Nagy
core +1 more source
Scientific Reports, 2017 The current study explored the Na+/K+-ATPase (NKA) inhibition-independent proarrhythmic mechanisms of cardiac glycosides (CGs) which are well-known NKA inhibitors. With the cytosolic Ca2+ chelated by EGTA and BAPTA or extracellular Ca2+ replaced by Ba2+,
Cai Hong Koh +11 more
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