Results 151 to 160 of about 2,339 (195)

Biochemical Characterisation and in vitro Antitumour Effect of Parotoid Gland Secretions of the Egyptian Toad (Bufo relgularis). [PDF]

Trop Life Sci Res
El-Naggar SA, Basyony MA, El-Wahsh HM, El-Feki SM, Kandyel RM.   +4 more
europepmc   +1 more source

Transcriptome Analysis of Triple-Negative HCC1937 and MDA-MB-231 Breast Cancer Cells Treated with <i>Kalanchoe pinnata</i> Revealed the Regulation of Migration and Invasion via the Downregulation of the Genes JAK2, ROCK1 and ROCK2. [PDF]

ACS Omega
Alvizo-Rodríguez C, Carrasco-Carballo A, López-Vázquez U, Hernández-Montes G, Hernández-Caballero ME.   +4 more
europepmc   +1 more source

[Biosynthesis of cardenolides and bufadienolides].

Postepy biochemii, 1973
openaire   +1 more source

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A novel bufadienolide synthesis

Steroids, 1974
Abstract A simple two-step synthesis of bufadienolides is reported. It consists in the addition of the dimethyl acetal of chloroketene to a steroidal 20-methylene 21-aldehyde and in the treatment of the resulting 2,2-dimethoxy 3-chloro 2,3-dihydropyran with sodium methoxide in dimethylsulfoxide.
A, Bélanger, P, Brassard, G, Dionne, C R, Engel   +3 more
openaire   +2 more sources

ChemInform Abstract: BUFADIENOLIDE 20. MITT. 14BETA‐CHLOR‐BUFADIENOLIDE

Chemischer Informationsdienst, 1973
AbstractDie Epoxide (Ia) und (Ib) reagieren mit Chlorwasserstoff in Chloroform zu den Chlorhydrinen (IIa) und (IIb).
Y. KAMANO, G. R. PETTIT
openaire   +1 more source

Unified Total Synthesis of Five Bufadienolides

Organic Letters, 2020
We report a unified total synthesis of five bufadienolides: bufalin (1), bufogenin B (2), bufotalin (3), vulgarobufotoxin (4), and 3-(N-succinyl argininyl) bufotalin (5). After the steroidal ABCD ring 8 was produced, the D ring was cross-coupled with a 2-pyrone moiety and stereoselectively epoxidized to generate 6.
Shinsuke Shimizu, Koichi Hagiwara, Hiroaki Itoh, Masayuki Inoue   +3 more
openaire   +2 more sources

Biosynthesis of bufadienolides—3β-hydroxycholanates as precursors in Bufo marinus bufadienolides synthesis

Biochemical Pharmacology, 1969
Abstract The biosynthesis of bufadienolides in toads ( Bufo marinus ) was investigated by measuring the radioactivity of resibufogenin, bufalin, marinobufagin and telocinobufagin in the venom following injection of some possible precursors labeled with 14 C or tritium.
C, Chen, M V, Osuch
openaire   +2 more sources

Bufadienolide glycosides and bufadienolides from the whole plants of Helleborus lividus, and their cytotoxic activity

Phytochemistry, 2020
Cytotoxicity-guided fractionation of the MeOH extract of Helleborus lividus Aiton ex Curtis (Ranunculaceae) resulted in the isolation of five undescribed bufadienolide glycosides and two undescribed bufadienolides, along with three known compounds. Their structures were determined by detailed spectroscopic analysis and hydrolysis studies.
Tomoki, Iguchi, Akihito, Yokosuka, Naoya, Tamura, Shingo, Takano, Yoshihiro, Mimaki   +4 more
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Bufadienolides and their antitumor activity

Natural Product Reports, 2011
Since 1998, a great number of bufadienolides have been reported from plants, animals and plant cell suspensions, as well as from fungi and bacteria cultures. This review summarizes both new bufadienolides and those obtained from new sources, together with data regarding the antitumor activity of bufadienolide derivatives.
Gao, Huimin, McKinnon, Ruxandra, Kopp, Brigitte, Wang, Zhimin   +3 more
openaire   +3 more sources