Results 161 to 170 of about 1,623 (201)

Biosynthesis of cardenolides, bufadienolides and steroid sapogenins

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1972
Abstract It has been known for several years that pregnenolone is the biogenetic precursor of hormones of the adrenal cortex and of progesterone in the animal kingdom. The route to the androgenous and oestrogenous hormones also goes via this intermediate. However, in the plant kingdom it was only later that the role of pregnenolone (1)
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Cytochrome P450 Mining for Bufadienolide Diversification

ACS Chemical Biology
Bufadienolides are a class of steroids with a distinctive α-pyrone ring at C17, mostly produced by toads and consisting of over 100 orthologues. They exhibit potent cardiotonic and antitumor activities and are active ingredients of the traditional Chinese medicine Chansu and Cinobufacini.
Xiaolai Lei, Xiaozheng Wang, Weiliang Xiong, Han Xiao, Yingchun Wu, Tingting Huang, Rubing Liang, Yiming Li, Shuangjun Lin   +8 more
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Bufadienolides from Urginea hesperia.

Planta medica, 2013
For the first time the composition of the bufadienolide complex in URGINEA HESPERIA Webb & Berth. has been investigated. From an extract of lyophilized plants, thirteen bufadienolides were isolated. By means of FAB-MS, (1)H-NMR, and (13)C-NMR studies the compounds were structurally elucidated as scillarenin, scilliphaeosidin, scillarenin-3- O-alpha- L ...
L, Krenn, M, Jambrits, B, Kopp
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Emerging Role of the Bufadienolides in Cardiovascular and Kidney Diseases

American Journal of Kidney Diseases, 2010
The bufadienolides are a group of steroid hormones that circulate in blood and are excreted in urine. They have the ability to inhibit the adenosine triphosphatase sodium-potassium pump (Na(+)-K(+)-ATPase), with predilection for its alpha1 isoform. This capability enables them to share with other cardiac glycosides the facility to cause an increase in ...
Jules B, Puschett, Enoch, Agunanne, Mohammad N, Uddin   +2 more
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Bufadienolides from Urginea pancration.

Planta medica, 2013
From bulbs of URGINEA PANCRATION (Steinh.) G. de Philippe (Hyacinthaceae) 5 bufadienolides were isolated by a combination of column and droplet counter-current chromatography; their structures were elucidated mainly by FAB-MS and (1)H- and (13)C-NMR spectroscopy.
B, Kopp, M, Unterluggauer, W, Robien, W, Kubelka   +3 more
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Comparative Activity of Bufadienolides

Journal of Medicinal and Pharmaceutical Chemistry, 1961
K K, CHEN, F G, HENDERSON
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Adsorption to activated charcoal and polarity of cardenolides and bufadienolides

Experientia, 1974
Die Adsorption von 10 Herzglykosiden und Geninen an Aktivkohle wurde untersucht. Es zeigte sich, dass mit zunehmender Polaritat der Substanzen die zur Adsorption benotigten Kohlemengen anwuchsen.
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[Progress in biotransformation of triptolides and bufadienolides].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2004
The latest results from our research group in the biotransformation of triptolides and bufadienolides were reviewed. The trends in the development of biotransformation in the future were also briefly discussed.
Min, Ye, Li-Li, Ning, Ji-Xun, Zhan, Hong-Zhu, Guo, De-An, Guo   +4 more
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Bufadienolides—19

Tetrahedron, 1975
Y. Kamano, G.R. Pettit, P. Brown, M. Inoue   +3 more
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Bufadienolides. 11. Bufalin and resibufogenin

The Journal of Organic Chemistry, 1970
G R, Pettit, L E, Houghton, J C, Knight, F, Bruschweiler   +3 more
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