Results 161 to 170 of about 2,339 (195)

Bufadienolides from animal and plant sources

Phytochemistry, 1998
Abstract Naturally occurring bufadienolides, which were isolated from both animal and plant sources and structurally elucidated in the period from 1967–1995, are reviewed and compiled.
Krenn, Liselotte, Kopp, Brigitte
openaire   +3 more sources

Bufadienolides from Urginea maritima from Egypt

Phytochemistry, 1996
Forty-one bufadienolides were isolated from the bulbs of Urginea maritima agg. from Egypt; 26 of them are new natural compounds. Structure elucidation was performed by comparison with authentic substances or by means of 1H, 13C NMR and FAB mass spectroscopy.
B, Kopp, L, Krenn, M, Draxler, A, Hoyer, R, Terkola, P, Vallaster, W, Robien   +6 more
openaire   +2 more sources

Bufadienolides from Urginea hesperia.

Planta medica, 2013
For the first time the composition of the bufadienolide complex in URGINEA HESPERIA Webb & Berth. has been investigated. From an extract of lyophilized plants, thirteen bufadienolides were isolated. By means of FAB-MS, (1)H-NMR, and (13)C-NMR studies the compounds were structurally elucidated as scillarenin, scilliphaeosidin, scillarenin-3- O-alpha- L ...
L, Krenn, M, Jambrits, B, Kopp
openaire   +4 more sources

Endogenous Bufadienolide, Blood Pressure and Alcohol Withdrawal

Current Hypertension Reviews, 2021
Background and Objective: Previously, it was demonstrated that marinobufagenin (MBG) is implicated in the development of ethanol withdrawal in rats. It has been shown that ethanol withdrawal is associated with a pressor response in the alcoholics. We hypothesized that elevated levels of sodium pump ligand, MBG, would underline the increase in systolic
Vladimir A. Kashkin, Alexei Y. Egorov, Evgeniy M. Krupitsky, Alexei Y. Bagrov   +3 more
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High resolution mass spectrometry. Bufadienolides—II.

Organic Mass Spectrometry, 1972
AbstractComplete low resolution mass spectra and high resolution data for selected important peaks are presented and discussed for a series of naturally occurring 14β, 15β‐epoxybufadienolides (toad poisons) and their derivatives. The compounds examined were resibufogenin, marinobufagin, cinobufagin, desacetylcinobufagin, cinobufotalin ...
Peter Brown, Yoshiaki Kamano, George R. Pettit   +2 more
openaire   +1 more source

One new bufadienolide from Chinese drug “Chan'Su”

Journal of Asian Natural Products Research, 2008
A new bufadienolide named 16beta-acetoxy-bufarenogin (1), together with six known bufadienolides, namely, 11alpha,12beta-dihydroxy-bufalin (2), bufotalin (3), hellebrigenin (4), desacetylbufotalin (5), gamabufotalin (6), and resibufagin (7) were isolated from Chan'Su. Of these, 2 was a new natural product.
Li, Qiao, Yong-Fu, Huang, Jia-Qing, Cao, Yu-Zhi, Zhou, Xiu-Lan, Qi, Yue-Hu, Pei   +5 more
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New bufadienolides from Urginea maritima sensu strictu

Fitoterapia, 2000
Two new bufadienolides, 11 alpha-acetylgamabufotalin 3-O-(4-O-beta-D-glucosyl)-alpha-L-rhamnoside (1) and 11 alpha-hydroxyscilliglaucoside (2), were isolated from bulbs of hexaploid Urginea maritima and identified by means of FAB-MS, (1)H-NMR and (13)C-NMR studies.
Krenn, Liselotte, Jelovina, Martina, Kopp, Brigitte   +2 more
openaire   +2 more sources

Ecdysteroids and bufadienolides from Helleborus torquatus (Ranunculaceae)

Phytochemistry, 2001
Three bufadienolides, hellebortin A (5-[beta-D-glucopyranosyloxy]-10,14,16-trihydroxy-19-nor-[5beta,10beta,14beta,16beta]-bufa-3,20,22-trienolide [1]), hellebortin B (5-[beta-D-glucopyranosyloxy]-3,4-epoxy-14-hydroxy-19-oxo-bufa-20,22-dienolide [2]) and hellebortin C (5-[beta-D-glucopyranosyloxy]-3,4-epoxy-10,14-dihydroxy-19-nor-bufa-20,22-dienolide [3]
Y, Meng, P, Whiting, V, Sik, H H, Rees, L, Dinan   +4 more
openaire   +2 more sources

Cytochrome P450 Mining for Bufadienolide Diversification

ACS Chemical Biology
Bufadienolides are a class of steroids with a distinctive α-pyrone ring at C17, mostly produced by toads and consisting of over 100 orthologues. They exhibit potent cardiotonic and antitumor activities and are active ingredients of the traditional Chinese medicine Chansu and Cinobufacini.
Xiaolai Lei, Xiaozheng Wang, Weiliang Xiong, Han Xiao, Yingchun Wu, Tingting Huang, Rubing Liang, Yiming Li, Shuangjun Lin   +8 more
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Structure of the bufadienolide bufotalin

Journal of the Chemical Society D: Chemical Communications, 1970
Mass spectral and 1H n.m.r. evidence, coupled with degradation of bufotalin to 3β-acetoxybufotalien (II), in turn prepared by total synthesis, provide unequivocal support for the assignment of structure (I) to bufotalin.
George R. Pettit, Peter Brown, Fred Bruschweiler, Leonard E. Houghton   +3 more
openaire   +1 more source