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Bufalin for an innovative therapeutic approach against cancer [PDF]
Pharmacological Research, 2022 peer reviewedBufalin is an endogenous cardiotonic steroid, first discovered in toad venom but also found in the plasma of healthy humans, with anti-tumour activities in different cancer types. The current review is focused on its mechanisms of action and
Sven Saussez +2 more
exaly +2 more sources
Bufalin Induces Lung Cancer Cell Apoptosis via the Inhibition of PI3K/Akt Pathway
International Journal of Molecular Sciences, 2012 Bufalin is a class of toxic steroids which could induce the differentiation and apoptosis of leukemia cells, and induce the apoptosis of gastric, colon and breast cancer cells. However, the anti-tumor effects of bufalin have not been demonstrated in lung
Enze Li +6 more
exaly +2 more sources
International Journal of Molecular Sciences, 2013 The traditional Chinese medicine bufalin, extracted from toad’s skin, has been demonstrated to exert anticancer activities in various kinds of human cancers.
Yan-Hua Xie +9 more
exaly +2 more sources
Nano LettersBufalin is a promising active ingredient in traditional Chinese medicine but has shown limited anticancer applications due to its toxicity. Here, we report BCNPs@gel, a bufalin-containing CaCO3 nanoparticle hydrogel, for enhancing cancer treatment ...
Lin Mei, Yongkang Yu, Hanjie Zhang
exaly +2 more sources
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