Results 41 to 50 of about 185,747 (240)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Random Forests Relay Selector in Buffer-Aided Cooperative Networks
IEEE AccessThis paper presents a data-driven Random Forest (RF) framework for the joint relay–link selection and buffer management problem in buffer-aided cooperative relay networks, with the goal of minimizing outage probability.
Mohammad Alkhawatrah
doaj +1 more source
International Journal of Health Geographics, 2007 Background There is increasing interest in examining the influence of the built environment on physical activity. High-resolution data in a geographic information system is increasingly being used to measure salient aspects of the built environment and ...
Hall Alexander W +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Avian response to conservation buffers in agricultural landscapes during winter
Wildlife Society Bulletin, 2014 Native herbaceous vegetation cover along row‐crop field edges (i.e., field buffers) increases breeding densities of many bird species. However, the effect of field buffers on bird species during the non‐breeding season is less understood.
Kristine O. Evans +8 more
doaj +1 more source
Polyamines Counteract Carbonate-Driven Proteasome Stalling in Alkaline Conditions
Biomolecules, 2020 Cancer cells tend to increase intracellular pH and, at the same time, are known to intensively produce and uptake polyamines such as spermine. Here, we show that various amines, including biogenic polyamines, boost the activity of proteasomes in a dose ...
Anna A. Kudriaeva +5 more
doaj +1 more source
, 2020 Abstract Chapter 7 discusses the buffer abstraction in detail. Buffers are a higher-level abstraction that hides the underlying details of memory management from an application. This chapter describes how to allocate and access the contents of a buffer both in our host programs and in our kernels running on a device.
James Reinders +5 more
openaire +1 more source