Results 51 to 60 of about 582,767 (331)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

A Systems Approach to Identifying Hazards in the Management of Vegetative Buffers for the Protection of Drinking Water Quality

Environmental Sciences Proceedings, 2023
Using ecosystem services provided by stream buffers has the potential to complement conventional engineering solutions, such as water treatment, and reduce public health risks to consumers.
Hew Cameron Merrett, Jao Jia Horng
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Buffered 4% Articaine Reduces Pain and Enhances Anesthesia in Maxillary Third Molar Extractions: A Randomized, Double-Blind Split-Mouth Study

Biomedicines
Background/Objectives: Buffered local anesthetics are suggested to enhance patient comfort and anesthetic efficacy during dental procedures. However, their advantages over non-buffered solutions in maxillary third molar extractions remain under ...
Henning Staedt, Victor Palarie, Diana Heimes, Peter Ottl, Shengchi Fan, Peer W. Kämmerer   +5 more
doaj   +1 more source

Riparian Functional Assessment Phase Two Summary [PDF]

, 2014
This report contains data regarding the drainage area, restoration strategy and banks sampled of three Waller Creek locations.In an effort to assess the response of degraded riparian buffers to the cessation of the main disturbance regime (mowing) and ...
González, Ana, Richter, Aaron
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Partially shared buffers with full or mixed priority [PDF]

, 2011
This paper studies a finite-sized discrete-time two-class priority queue. Packets of both classes arrive according to a two-class discrete batch Markovian arrival process (2-DBMAP), taking into account the correlated nature of arrivals in heterogeneous ...
Dieter Fiems, Herwig Bruneel, Joris Walraevens, null null, Thomas Demoor   +4 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Arañas en cultivos de lechuga con cilantro como planta acompañante

AIA Avances en Investigación Agropecuaria
Objetivo. Este estudio busca relevar la composición, abundancia, gremios, variaciones estacionales y diversidad de arañas en cultivos de lechuga con cilantro como planta acompañante. Materiales y métodos.
Victoria Fernández Acevedo, Andrea Armendano   +1 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source