Results 101 to 110 of about 5,072,317 (340)

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Air-Entraining Effect on Rheological Properties of Cement-Based Mixtures

Advances in Materials Science and Engineering
The rheological properties and stability of cement-based materials determine the technological properties of concrete mixtures and significantly influence concrete properties.
Aigerim Tolegenova, Gintautas Skripkiunas, Lyudmyla Rishko, Kenzhebek Akmalaiuly   +3 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Effect of different buried depth on the disintegration characteristic of red-bed soft rock and the evolution model of disintegration breakage under cyclic drying-wetting

Scientific Reports
The disintegration of red-bed soft rock exhibits a strong correlation with various geological disasters. However, the investigation into the evolutionary mechanisms underlying disintegration breakage has not yet received extensive exploration.
Jun Zhang, Yang Guo, Kai Huang, Wei Cui, Zhaibang Ke, Xiaochuang Chen, Tengsheng Yue, Kun Gao   +7 more
doaj   +1 more source

Robotic Large-Scale Additive Manufacturing of Thermoplastics for Thin-Glass Composite Elements

Challenging Glass Conference Proceedings, 2022
The use of thin glass promises to enable a variety of construction industry pursuits. In addition to the ecological benefits of more efficient use of resources, architects can anticipate new design freedoms with thin glass. Based on the sandwich theory,
Daniel Pfarr, Christian Louter
doaj  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Large CO2 reduction and enhanced thermal performance of agro-forestry, construction and demolition waste based fly ash bricks for sustainable construction

Scientific Reports
The exhaust gases in production of burnt clay bricks is responsible for greenhouse gases (GHGs) emission which increase the carbon footprint in the ecosystem. Here, we report carbon emission and thermal performance based evaluation of 8 ft. × 9 ft.
Siddharth Singh, Soumitra Maiti, Ravindra Singh Bisht, Soraj Kumar Panigrahi, Sameer Yadav   +4 more
doaj   +1 more source

Methods for Dimensioning an Adhesive Joint for Use in Fluid-Filled Façade Element

Challenging Glass Conference Proceedings
Fluids in the cavity can be used to integrate additional functions into insulating glazing. However, the high permanent load exerted by the fluid on the glazing and surrounding components is problematic.
Alina Katzera, Michael Engelmann, Bernhard Weller   +2 more
doaj   +1 more source