Results 101 to 110 of about 2,074,218 (303)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

IFC-based calculation of the Flemish Energy Performance Standard [PDF]

open access: yes, 2009
This paper illustrates our findings concerning space based design methodologies and interoperability issues for today's Building Information Modeling (BIM) environments.
De Meyer, Ronald   +5 more
core   +1 more source

A new structural model for the Si(331)-(12x1) reconstruction [PDF]

open access: yes, 2008
A new structural model for the Si(331)-(12x1) reconstruction is proposed. Based on scanning tunneling microscopy images of unprecedented resolution, low-energy electron diffraction data, and first-principles total-energy calculations, we demonstrate that
B. Z. Olshanetsky   +8 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Tests of a reduced-scale experimental model of a building solar heating-cooling system [PDF]

open access: yes
An experimental solar heating and cooling system model has been built and operated, combining elements that are programmable (e.g., heating and cooling load of a building and collected solar energy) with experimental equipment.
Namkoong, D.
core   +1 more source

The application of predictive stochastic model based on Monte Carlo method in building energy saving renovation [PDF]

open access: yesArchives of Civil Engineering
: This research has established an energy consumption prediction model based on the Monte Carlo method to resolve the energy-saving transformation problem. First, simplify the building to construct the proposed model.
Juxian Xiao
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Building Energy Modeling in Airport Architecture Design

open access: yes, 2018
Energy efficiency and Building Energy Modeling are two successful approaches to architecture, engineering, construction and operation (AECO) programs. In recent year several education initiatives focusing on buildings energy management have been carried out to provide professional profiles with specific skills in technology, architecture, engineering ...
Maria Antonietta Esposito   +1 more
openaire   +2 more sources

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