Results 51 to 60 of about 132,806 (311)

Synthesis of bio-based building blocks from vegetable oils: a platform chemicals approach

open access: yesOléagineux, Corps gras, Lipides, 2013
This review reports the synthesis of various building blocks from vegetable oils in one or two-steps syntheses. Thiol-ene coupling allows to synthesize new biobased reactants with various function and functionality with reaction conditions in agreement ...
Desroches Myriam   +3 more
doaj   +1 more source

The Effect Of Thermal Insulation Of An Apartment Building On The Thermo-Hydraulic Stability Of Its Heating System

open access: yesSlovak Journal of Civil Engineering, 2015
The contribution aims to investigate the effect of the decreased thermal losses of an apartment building due to the thermal insulation of opaque external building constructions and the replacement of transparent constructions. It emphasizes the effect of
Kurčová Mária
doaj   +1 more source

A Theorem Prover for Scientific and Educational Purposes [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2018
We present a prototype of an integrated reasoning environment for educational purposes. The presented tool is a fragment of a proof assistant and automated theorem prover.
Mario Frank, Christoph Kreitz
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

2,2-difluorovinyl benzoates for diverse synthesis of gem-difluoroenol ethers by Ni-catalyzed cross-coupling reactions

open access: yesNature Communications, 2021
The gem-difluoroalkene functionality is relevant to drug design as it is a bioisostere of a carbonyl group. Here, the authors report the synthesis of 2,2-difluorovinyl benzoates as versatile building blocks for modular synthesis of gem-difluoroenol ...
Bingnan Du   +6 more
doaj   +1 more source

Covid-19 and Functionality: By Providing Social Distancing of Indoor Common Spaces in Residential Building

open access: yesJournal of Studies in Science and Engineering, 2021
Before the COVID-19 pandemic, people spent on average around 90% of their time indoors. Nowadays, more than ever, with work-from-home commands in place, it is important that they rethink the design and procedure of buildings.
Salahaddin Yasin Bapir   +1 more
doaj   +1 more source

Building confidence in the Dirac δ -function

open access: yesEuropean Journal of Physics, 2018
8 pages, 3 ...
Asim Gangopadhyaya, Constantin Rasinariu
openaire   +4 more sources

Relation between design requirements and building performance simulation [PDF]

open access: yes, 2006
The aim of this paper is to reveal the relation between basic design requirements and the use of building performance simulation in current design practice.
Struck, C.   +7 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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