Results 111 to 120 of about 901,725 (258)

Hybrid Revit and a new MCDM approach of energy effective nursing-home designed by natural stone and green insulation materials

open access: yesJournal of Civil Engineering and Management
The requisition for maintainable constructions has been greatly raising over the last several years. To fulfil the maintainability necessities of a construction, decisions or changes must be done to a construction in the course of the preconstruction ...
Figen Balo   +4 more
doaj   +1 more source

Does size matter? Experiences and perspectives of BIM implementation from large and SME construction contractors [PDF]

open access: yes, 2012
This paper presents the findings of a qualitative study into the experiences and perspectives of large and SME construction contractors towards the implementation of Building Information Modelling (BIM) within their organisations.
Bleanch, Paula   +2 more
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Analysis Framework for the Interaction Between Lean Construction and Building Information Modelling [PDF]

open access: yes
Building with Building Information Modelling (BIM) changes design and production processes. But can BIM be used to support process changes designed according to lean production and lean construction principles? To begin to answer this question we provide
Dave, Bhargav   +3 more
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Building information modelling for visualisation in AEC education [PDF]

open access: yes, 2005
This paper outlines the process used to introduce building information modelling into the academic curriculum of built environment students and reflects on the techniques used to ensure appropriate use of parametric tools for the purposes of ...
Horne, Margaret   +2 more
core   +1 more source

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