Results 71 to 80 of about 901,725 (258)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
MATEC Web of Conferences, 2018 Paper´s focus is on differences between traditional modelling in 2D software and modelling within the BIM technology. Research uncovers failures connected to the traditional way of designing and construction of project documentation.
Prušková Kristýna
doaj +1 more source
A Semantic Modelling Framework-Based Method for Building Reconstruction from Point Clouds
Remote Sensing, 2016 Over the past few years, there has been an increasing need for semantic information in automatic city modelling. However, due to the complexity of building structure, the semantic reconstruction of buildings is still a challenging task because it is ...
Qingdong Wang +4 more
doaj +1 more source
Investigation Into Informational Compatibility Of Building Information Modelling And Building Performance Analysis Software Solutions [PDF]
, 2015 There are significant opportunities for Building Information Modelling (BIM) to address issues related to sustainable and energy efficient building design.
Hyun, S +2 more
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
ARMAGH OBSERVATORY – HISTORIC BUILDING INFORMATION MODELLING FOR VIRTUAL LEARNING IN BUILDING CONSERVATION [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017 In this paper the recording and design for a Virtual Reality Immersive Model of Armagh Observatory is presented, which will replicate the historic buildings and landscape with distant meridian markers and position of its principal historic instruments ...
M. Murphy +5 more
doaj +1 more source
Building information modelling (BIM) implementation and remote construction projects: issues, challenges, and critiques. [PDF]
, 2012 The construction industry has been facing a paradigm shift to (i) increase productivity, efficiency, infrastructure value; quality and sustainability (ii) reduce lifecycle costs, lead times and duplications via effective collaboration and communication ...
Arayici, Y, Coates, SP, Egbu, CO
core
Non-uniform state space reconstruction and coupling detection
, 2010 We investigate the state space reconstruction from multiple time series derived from continuous and discrete systems and propose a method for building embedding vectors progressively using information measure criteria regarding past, current and future ...
Kugiumtzis, Dimitris, Vlachos, Ioannis
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source