Results 71 to 80 of about 902,578 (275)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
MATEC Web of Conferences, 2018 Paper´s focus is on differences between traditional modelling in 2D software and modelling within the BIM technology. Research uncovers failures connected to the traditional way of designing and construction of project documentation.
Prušková Kristýna
doaj +1 more source
A Semantic Modelling Framework-Based Method for Building Reconstruction from Point Clouds
Remote Sensing, 2016 Over the past few years, there has been an increasing need for semantic information in automatic city modelling. However, due to the complexity of building structure, the semantic reconstruction of buildings is still a challenging task because it is ...
Qingdong Wang +4 more
doaj +1 more source
ARMAGH OBSERVATORY – HISTORIC BUILDING INFORMATION MODELLING FOR VIRTUAL LEARNING IN BUILDING CONSERVATION [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017 In this paper the recording and design for a Virtual Reality Immersive Model of Armagh Observatory is presented, which will replicate the historic buildings and landscape with distant meridian markers and position of its principal historic instruments ...
M. Murphy +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Usefulness of VRML building models in a direction finding context [PDF]
, 2007 This paper describes an experiment which aims to examine the effectiveness and efficiency of a Virtual Reality Modelling Language (VRML) building model compared with equivalent architectural plans, for direction finding purposes.
Mackey, D, Murano, P
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Building information modelling (BIM) implementation and remote construction projects: issues, challenges, and critiques. [PDF]
, 2012 The construction industry has been facing a paradigm shift to (i) increase productivity, efficiency, infrastructure value; quality and sustainability (ii) reduce lifecycle costs, lead times and duplications via effective collaboration and communication ...
Arayici, Y, Coates, SP, Egbu, CO
core
Non-uniform state space reconstruction and coupling detection
, 2010 We investigate the state space reconstruction from multiple time series derived from continuous and discrete systems and propose a method for building embedding vectors progressively using information measure criteria regarding past, current and future ...
Kugiumtzis, Dimitris, Vlachos, Ioannis
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source