Results 101 to 110 of about 811,371 (313)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

R. G. Parsons Building site, 1962 -- 01

open access: yes, 1962
Building site for R. G.Parsons Applied Science Building, 1962.
Swinburne College of Technology
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

MIT: Building Technology Program

open access: yes
The Building Technology Program at the Massachusetts Institute of Technology (MIT) is an interdisciplinary program, bringing together researchers from the Department of Architecture, the Department of Civil and Environmental Engineering, and the ...

core  

Business Arts Building construction, 1975

open access: yes, 1974
View looking down John Street with the Business Arts Building (BA) under construction ...
Swinburne College of Technology
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

NEMO (National Center for Science and Technology)

open access: yes, 1992
View of sloped top floor "piazza" and seating with pedestrian ramp to the right; road tunnel passing underneath and NEMO on the brick-clad tower; In 1923, the Labor Museum was founded by artist Herman Heijenbrock.
Renzo Piano Building Workshop
core  

Contribution to the Medieval Building Technology Based on the Reconstruction of a Rounded Church

open access: yesEXARC Journal, 2012
This article presents the experimental archaeological project to build a medieval rotunda reconstruction using rough stone building technology. Here, a medieval rotunda reconstruction is presented by contemporary building technology.
Ákos Nemcsics
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Publications on Canadian building technology

open access: yes, 1978
This Digest is intended to serve as a short introduction to the main Canadian sources of printed information on building technology. The places to begin a search for published information or for directories and periodicals are libraries, either public ...
Williams, G. P., Carson, E. R.
core  

Home - About - Disclaimer - Privacy