Results 111 to 120 of about 811,371 (313)
Building Better Conservation Organisations with Blockchain Technology
Blockchain technology can enable non-profit organisations (NPOs) to create a large, diverse, and engaged community of donors and stakeholders in an autonomous and transparent manner [...]
Rand Kwong Yew Low +1 more
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
AD Building, BA Building and Library viewed from above, Open Day, 2015
Administration Building (AD), Business and Arts Building (BA) and Library viewed from above on Open Day 2015, Hawthorn Campus, 2 August 2015.
Swinburne University of Technology
core
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Entrance to Art School Building, circa 1970
Entrance to the Art School Building circa ...
Swinburne Institute of Technology
core
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Business Arts Building construction, 1972 -- 01
Foundation works for the Business Arts Building (BA), 1972.
Swinburne College of Technology
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Integrated Simulation for Building Design: an Example State-of-the-Art System
This paper outlines the current state-of-the-art in integrated building simulation. The ESP-r system is used as an example where integrated simulation is a core philosophy behind the development.
Hensen, J.L.M. +3 more
core
Recent advances in the development of MOST: an open-source, vendor and technology independent toolkit for building monitoring, data preprocessing and visualization [PDF]
The present contribution describes approaches for visualizing building related data (temperature, energy use, etc.). A web based visualization framework is presented and a number of use cases are demonstrated (i.e.
Mahdavi, A. +3 more
core

