Results 51 to 60 of about 563,955 (265)

Transition from n50 to actual air exchange dependent on climatic conditions [PDF]

MATEC Web of Conferences, 2019
The knowledge of the air flow and air exchange in the building is critical both on the design and operation stage of the building. Infiltration of air interferes with the mechanical ventilation and determines the proper functioning of the natural ...
Kisilewicz Tomasz, Nowak-Dzieszko Katarzyna, Rojewska-Warchał Małgorzata   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Satisfaction and representations of raw earth habitat: a case study of Auroville, India

Journal of Asian Architecture and Building Engineering
This exploratory study presents, for the first time, an analysis of how residential satisfaction (RS) can be related to earthen building materials.
Nourredine Kebaili, Mohamed Saci, Youcef Kehila, Rafik Bensalem   +3 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Green building future: algal application technology

Journal of Sustainable Construction Materials and Technologies
In the context of rising global energy demands driven by population growth and urbanization, the construction industry significantly contributes to greenhouse gas emissions during the construction phase and subsequent energy consumption.
Özgür Eren Zariç, İrem Yeşildağ, Abuzer Çelekli   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Building m-health technology to promote breastfeeding

Revista de Enfermagem da UFPI
Objective: to develop an m-health technology to promote breastfeeding in nursing mothers. Methods: methodological study, carried out from February 2020 to July 2021. Technological development application, following Pressman's prototyping model.
Jéssika Roberta Firme de Moura Santos, Maria Alzete de Lima, Ana Larissa Gomes Machado, Edina Araújo Rodrigues Oliveira, Adriele de Almeida Brito, Milena Leite Veloso, Luisa Helena de Oliveira Lima   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source