Results 51 to 60 of about 3,636,192 (303)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Advances in Cold-Climate-Responsive Building Envelope Design: A Comprehensive Review
BuildingsExtreme low temperatures, heavy snowfall, ice accumulation, limited daylight, and increased energy consumption in cold climates present significant challenges but also offer opportunities for improving building efficiency.
Zahra Al-Shatnawi +3 more
doaj +1 more source
Jurnal Pendidikan Teknologi dan Kejuruan, 2019 This study investigated socio-economic determinants of students’ academic achievement in building technology in North-central Nigeria. It was a quest to probe into the incessant cases of students’ poor achievement in building technology to identify ...
Yahaya Ibn Salihu, Nordin Safarin Mohd
doaj +1 more source
Effect of α: Phase Nano Al2O3 and Rice Husk Ash in Cement Mortar
Advances in Civil Engineering, 2022 The study focused on the investigation of the influence of α-phase nano Al2O3 (NA) and M-sand as a fine aggregate on the partial replacement of cement by micro rice husk ash (MRHA) to enhance the mechanical properties and durability of mortar and achieve
Alexander Gladwin Alex +3 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Climate responsive and safe earthquake construction: a community building a school
Journal of Natural Resources and Development, 2011 This article outlines environment friendly features, climate responsive features and construction features of a prototype school building constructed using green building technology.
Hari Darshan +3 more
doaj +1 more source
, 2009 In 1995, Robin Evans points out in his book The Projective Cast how the development of techniques changed architecture and the space inhabited in times of Gothic and early Renaissance. We see a parallel phenomenon today, where the interplay of technology
Ramsgaard Thomsen, Mette, Tamke, Martin
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Rewritable routines in human interaction with public technology [PDF]
, 1997 In this paper, the cognitive ergonomics of using public technology is investigated. A methodology for predicting human error with technology has been developed.
Baber, C, Stanton, NA
core