Results 21 to 30 of about 439,953 (245)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The LIGHTVAN: Mobile light laboratory

Spool, 2014
The 'LIGHTVAN' research aims to optimize the lighting design for healthy schools and modern senior housing and care homes with regards to the use of light as a cheap and important source of energy. A multi-functional mobile light laboratory was built
Truus Hordijk, Marcel Bilow, Marielle Aarts, Alexander Rosemann   +3 more
doaj   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Nighttime Mobile Laser Scanning and 3D Luminance Measurement: Verifying the Outcome of Roadside Tree Pruning with Mobile Measurement of the Road Environment

ISPRS International Journal of Geo-Information, 2020
Roadside vegetation can affect the performance of installed road lighting. We demonstrate a workflow in which a car-mounted measurement system is used to assess the light-obstructing effect of roadside vegetation. The mobile mapping system (MMS) includes
Mikko Maksimainen, Matti T. Vaaja, Matti Kurkela, Juho-Pekka Virtanen, Arttu Julin, Kaisa Jaalama, Hannu Hyyppä   +6 more
doaj   +1 more source

Built Environments

, 2023
AbstractThe built environment consists of the human-made physical parts of the environment, including homes, buildings, streets, open spaces, and infrastructure. This chapter will focus on analyzing global infrastructure datasets.
openaire   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Multi-agent systems in climate-resilient land-use planning: a review

International Journal of Digital Earth
With the gradual evolution of human land-use patterns, climate and land-use change have become increasingly intertwined, requiring integrated strategies for sustainable management.
Yinuo Zhou, Qi Han, Shahryar Sarabi, Bauke de Vries   +3 more
doaj   +1 more source

Cleanliness in context: reconciling hygiene with a modern microbial perspective

Microbiome, 2017
The concept of hygiene is rooted in the relationship between cleanliness and the maintenance of good health. Since the widespread acceptance of the germ theory of disease, hygiene has become increasingly conflated with sterilization. In reviewing studies
Roo Vandegrift, Ashley C. Bateman, Kyla N. Siemens, May Nguyen, Hannah E. Wilson, Jessica L. Green, Kevin G. Van Den Wymelenberg, Roxana J. Hickey   +7 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source