Results 41 to 50 of about 627,272 (298)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

New Technologies for the Prevention of Excavation Damages

open access: yesGeoforum Perspektiv, 2020
Inaccurate and even lack of documentation is the main cause of excavation damage in Denmark. A pipe excavation is most often an expensive and time-consuming affair, and therefore both pipe owners and excavators strive to avoid it as much as possible ...
Lasse Hedegaard Hansen   +3 more
doaj   +1 more source

A disaster resilient built environment in urban cities [PDF]

open access: yes, 2015
– This research aims at making recommendations to empower the Sri Lankan local governments in creating a disaster resilient built environment. Disasters make a huge impact on the built environment.
Amaratunga, Dilanthi   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Master of Faculty of Built Environment [PDF]

open access: yes, 2020
Faculty of Built Environment Bachelor's Degree Certificate yr 2020 for 8 ...
Universiti Malaysia Sarawak, Faculty of Built Environment
core  

Built environment at DEQ. Spanish [PDF]

open access: yes, 2023
Video explaining the Oregon Department of Environmental Quality's Built Environment Program and listening sessions with community members.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository ...

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Nighttime Mobile Laser Scanning and 3D Luminance Measurement: Verifying the Outcome of Roadside Tree Pruning with Mobile Measurement of the Road Environment

open access: yesISPRS International Journal of Geo-Information, 2020
Roadside vegetation can affect the performance of installed road lighting. We demonstrate a workflow in which a car-mounted measurement system is used to assess the light-obstructing effect of roadside vegetation. The mobile mapping system (MMS) includes
Mikko Maksimainen   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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