Results 31 to 40 of about 3,007,514 (284)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Visualisation techniques, human perception and the built environment [PDF]
, 2009 Historically, architecture has a wealth of visualisation techniques that have evolved throughout the period of structural design, with Virtual Reality (VR) being a relatively recent addition to the toolbox.
Johnson, Angie
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
ISPRS International Journal of Geo-Information, 2020 Roadside vegetation can affect the performance of installed road lighting. We demonstrate a workflow in which a car-mounted measurement system is used to assess the light-obstructing effect of roadside vegetation. The mobile mapping system (MMS) includes
Mikko Maksimainen +6 more
doaj +1 more source
Why people use their cars while the built environment imposes cycling [PDF]
, 2013 Residing in a high-density, diverse, and accessible neighborhood tends to be associated with less car use, more public transport, and more cycling and walking.
Derudder, Ben +2 more
core +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cleanliness in context: reconciling hygiene with a modern microbial perspective
Microbiome, 2017 The concept of hygiene is rooted in the relationship between cleanliness and the maintenance of good health. Since the widespread acceptance of the germ theory of disease, hygiene has become increasingly conflated with sterilization. In reviewing studies
Roo Vandegrift +7 more
doaj +1 more source
, 2023 AbstractThe built environment consists of the human-made physical parts of the environment, including homes, buildings, streets, open spaces, and infrastructure. This chapter will focus on analyzing global infrastructure datasets.
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Multi-agent systems in climate-resilient land-use planning: a review
International Journal of Digital EarthWith the gradual evolution of human land-use patterns, climate and land-use change have become increasingly intertwined, requiring integrated strategies for sustainable management.
Yinuo Zhou +3 more
doaj +1 more source