Results 81 to 90 of about 3,007,514 (284)

A completely transparent, adhesively bonded soda-lime glass block masonry system

Journal of Facade Design and Engineering, 2015
A pioneering, all transparent, self-supporting glass block facade is presented in this paper. Previously realized examples utilize embedded metal components in order to obtain the desired structural performance despite the fact that these elements ...
Faidra Oikonomopoulou, Fred Veer, Rob Nijsse, K. Baardolf   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tools of the Architect

Spool, 2018
What tools, procedures, and methods do architects use? The triptychs on display show their approach both in analytical and designerly ways. The first panel of each triptych represents an architectural question; the second panel represents a method.
Willemijns Wilms Floet, Klaske Havik, Tom Avermaete, Jorge Meíja Hernández   +3 more
doaj   +3 more sources

Three-Dimensional Multitemporal Game Engine Visualizations for Watershed Analysis, Lighting Simulation, and Change Detection in Built Environments

ISPRS International Journal of Geo-Information
This study explores the reuse of high-resolution 3D spatial datasets for multiple urban analyses within a game engine environment, aligning with circular economy principles in sustainable urban planning. The work is situated in two residential test areas
Heikki Kauhanen, Toni Rantanen, Petri Rönnholm, Osama Bin Shafaat, Kaisa Jaalama, Arttu Julin, Matti Vaaja   +6 more
doaj   +1 more source

Users’ Perceptions on Pedestrian Prioritized Neighborhoods: a study on Terrace Row Housing Estates in Malaysia

International Journal of Built Environment and Sustainability, 2015
Malaysia is currently enjoying an overhang of housing supply. The focus is gradually shifting from providing just a mere shelter to something more socially.
Tareef Hayat Khan, Abubakar Danladi Isah, Elahe Anjomshoaa, Soheil Sabri   +3 more
doaj   +1 more source

Sustainable Approaches in Built Environment in Preparing for Global Environmental Change [PDF]

, 2014
No ...
DOLA, KAMARIAH, Pour Rahimian, Farzad
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Rethinking Space Design Standards Toward Quality Affordable Housing In Malaysia

MATEC Web of Conferences, 2016
Provision of affordable housing is important to low- and middle-income population. A fit form of house will not only fulfil a basic human need for shelter, but it also contributes to physical and psychological well-being of the occupants.
Ishak Nor Haniza, Mohd Ariffin Ati Rosemary, Sulaiman Raha, Mohd Zailani Muhammad Najib   +3 more
doaj   +1 more source

Future of built environment [PDF]

, 2012
FINAL-YEAR Architecture student Chong Chun Jiat had not enjoyed a good night's sleep in days. As the programme director of the 24th Architectural Workshop - the recent instalment of the most anticipated event among architecture students in Malaysia ...
Uda Nagu, Suzieana
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